Dimethyl (2S)-2-hydroxysuccinate

Basic Information

View in Editor

CAS Number

617-55-0

Molecular Formula

C6H10O5

Molecular Weight

162.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

249.6℃ at 760 mmHg

Density

1.223 g/mL at 25 °C

Refractive Index

n20/D 1.435(lit.)

SMILES

View in Editor

COC(=O)CC(C(=O)OC)O

InChI

InChI=1S/C6H10O5/c1-10-5(8)3-4(7)6(9)11-2/h4,7H,3H2,1-2H3/t4-/m0/s1

InChIKey

YSEKNCXYRGKTBJ-BYPYZUCNSA-N

LogP

-0.9166000000000003

Topological Polar Surface Area

72.83 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

153

Safety Information

View Safety Information

GHS Hazard Pictograms

H226

H317

H318

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

EC 432-310-0
O10223
CHEBI:228306
Dimethyl (S)-2-hydroxysuccinate
DTXSID50892497
(S)-Dimethyl 2-hydroxysuccinate
AKOS015850984
dimethyl-l-malate
Dimethyl (S)-(-) malate
(-)-dimethyl malate
di-methyl (s)-malate
L-(-)-Malic acid dimethylester
M1343
CS-W007994
Dimethyl L-malate
617-55-0
1,4-dimethyl (2S)-2-hydroxybutanedioate
L-(-)-Malic Acid Dimethyl Ester
Dimethyl (S)-(-)-malate, 98%
L-(-)-Apple Acid Dimethyl Ester
(s)-(-)-dimethyl malate
Dimethyl (2S)-2-hydroxybutanedioate
Butanedioic acid, hydroxy-, dimethyl ester, (2S)-
SCHEMBL1823637
CS-17326
(S)-Dimethyl2-hydroxysuccinate
J-520343
3-AMINO-4-M-TOLYLBUTANOICACID
MFCD00066215
EN300-198444
Dimethyl (2S)-2-hydroxysuccinate

MDL Number

MFCD00066215

Customs Code

2918199090

FAQ

What are the physical and chemical properties of Dimethyl (2S)-2-hydroxysuccinate (CAS: 617-55-0)?

Dimethyl (2S)-2-hydroxysuccinate has a crystalline form with a molecular weight of approximately 182.24 g/mol. It is slightly soluble in water and has good solubility in organic solvents. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution and esterification reactions.

How is Dimethyl (2S)-2-hydroxysuccinate (CAS: 617-55-0) typically synthesized?

Dimethyl (2S)-2-hydroxysuccinate is typically synthesized through the reaction of (2R,3S)-3,4-dihydroxybutanedioic acid with dimethyl sulfate or through the hydrolysis of dimethyl (2S)-2-hydroxybutanedioate. The synthesis often requires the use of a catalyst and achieves high selectivity and yield.

What industries use Dimethyl (2S)-2-hydroxysuccinate (CAS: 617-55-0)?

Dimethyl (2S)-2-hydroxysuccinate is used in the pharmaceutical industry for intermediate synthesis in the production of certain drugs. It is also utilized in the polymer industry for modification of polymer properties and in the sensor industry for enhancing detection sensitivity.

What precautions should be taken when handling Dimethyl (2S)-2-hydroxysuccinate (CAS: 617-55-0)?

When handling Dimethyl (2S)-2-hydroxysuccinate, appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn to prevent skin and eye contact. It should be stored in a well-ventilated area and handled in a fume hood to avoid inhaling vapors. In case of spills, clean up with appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions.