Dimethyl (2S)-2-hydroxysuccinate(CAS: 617-55-0)

Dimethyl (2S)-2-hydroxysuccinate has a crystalline form with a molecular weight of approximately 182.24 g/mol. It is slightly soluble in water and has good solubility in organic solvents. The compound exhibits moderate reactivity, particularly towards nucleophilic substitution and esterification reactions.

Dimethyl (2S)-2-hydroxysuccinate is typically synthesized through the reaction of (2R,3S)-3,4-dihydroxybutanedioic acid with dimethyl sulfate or through the hydrolysis of dimethyl (2S)-2-hydroxybutanedioate. The synthesis often requires the use of a catalyst and achieves high selectivity and yield.

Dimethyl (2S)-2-hydroxysuccinate is used in the pharmaceutical industry for intermediate synthesis in the production of certain drugs. It is also utilized in the polymer industry for modification of polymer properties and in the sensor industry for enhancing detection sensitivity.

When handling Dimethyl (2S)-2-hydroxysuccinate, appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn to prevent skin and eye contact. It should be stored in a well-ventilated area and handled in a fume hood to avoid inhaling vapors. In case of spills, clean up with appropriate absorbent materials and consult the Safety Data Sheet (SDS) for further instructions.