2-[4-(Benzyloxy)phenyl]ethanol

Basic Information

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CAS Number

61439-59-6

Molecular Formula

C15H16O2

Molecular Weight

228.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

87-88 ºC

Boiling Point

379.1°C at 760 mmHg

Density

1.116±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CC=C(C=C1)COC2=CC=C(C=C2)CCO

InChI

InChI=1S/C15H16O2/c16-11-10-13-6-8-15(9-7-13)17-12-14-4-2-1-3-5-14/h1-9,16H,10-12H2

InChIKey

JCUJAHLWCDISCC-UHFFFAOYSA-N

LogP

2.8004000000000007

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

191

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2-[4-(Benzyloxy)phenyl]ethanol
CS-0156170
Benzeneethanol, 4-(phenylmethoxy)-
EN300-6498110
1-benzyloxy-4-(2-hydroxyethyl)benzene
4-(Benzyloxy)phenethyl alcohol
3,4-Diaminotoluenedihydrochloride
2-[4-(benzyloxy)phenyl]ethan-1-ol
SY062276
JCUJAHLWCDISCC-UHFFFAOYSA-N
2-(4-phenylmethoxyphenyl)ethanol
MFCD00017532
SCHEMBL5700
61439-59-6
4-Benzyloxyphenyl ethyl alcohol
FT-0608582
NS00022501
AMY15506
p-(Benzyloxy)phenethyl alcohol
4-benzyloxy phenethyl alcohol
2-(4-(Benzyloxy)phenyl)ethanol
2-(4-Benzyloxyphenyl)-ethanol
AKOS005207242
4-Benzyloxyphenylethyl alcohol
2-(p-Benzyloxyphenyl)ethanol
DTXSID80210382
AS-10654
EINECS 262-795-2
4-Benzyloxyphenethyl Alcohol
A848397
2-(4-Benzyloxyphenyl)ethanol

MDL Number

MFCD00017532

Customs Code

2909499000

FAQ

What are the physical and chemical properties of 2-[4-(Benzyloxy)phenyl]ethanol (CAS: 61439-59-6)?

2-[4-(Benzyloxy)phenyl]ethanol is a clear, colorless liquid with a molecular weight of approximately 252.29 g/mol. It has a pKa of around 10.5 and is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. This compound is known for its low reactivity under normal conditions, making it stable in air and common solvents.

How is 2-[4-(Benzyloxy)phenyl]ethanol (CAS: 61439-59-6) typically synthesized?

2-[4-(Benzyloxy)phenyl]ethanol can be synthesized by reacting benzyl bromide with p-hydroxybenzaldehyde in the presence of sodium hydroxide. The reaction yields a mixture that can be purified by recrystallization. Alternatively, it can be prepared from 4-benzyloxybenzaldehyde through reduction with sodium borohydride, followed by hydrolysis.

What industries use 2-[4-(Benzyloxy)phenyl]ethanol (CAS: 61439-59-6)?

2-[4-(Benzyloxy)phenyl]ethanol is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer or intermediate, and in the chemical sensor field for its ability to act as a chromogenic reagent.

What precautions should be taken when handling 2-[4-(Benzyloxy)phenyl]ethanol (CAS: 61439-59-6)?

When handling 2-[4-(Benzyloxy)phenyl]ethanol, appropriate personal protective equipment (PPE) should be worn, including gloves and safety goggles. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up carefully following standard procedures, and the area should be ventilated. For more detailed safety information, refer to the Safety Data Sheet (SDS).