Compound Q&A

How is 2-[4-(Benzyloxy)phenyl]ethanol (CAS: 61439-59-6) typically synthesized?

Answer

2-[4-(Benzyloxy)phenyl]ethanol
2-[4-(Benzyloxy)phenyl]ethanol can be synthesized by reacting benzyl bromide with p-hydroxybenzaldehyde in the presence of sodium hydroxide. The reaction yields a mixture that can be purified by recrystallization. Alternatively, it can be prepared from 4-benzyloxybenzaldehyde through reduction with sodium borohydride, followed by hydrolysis.

About

CAS No 61439-59-6
English Name 2-[4-(Benzyloxy)phenyl]ethanol
Molecular Formula C15H16O2
Molecular Weight 228.29 g/mol
SMILES C1=CC=C(C=C1)COC2=CC=C(C=C2)CCO
InChIKey JCUJAHLWCDISCC-UHFFFAOYSA-N
Last Updated: 2025-10-10 13:51

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