2-Amino-3-nitrophenol

Basic Information

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CAS Number

603-85-0

Molecular Formula

C6H6N2O3

Molecular Weight

154.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

212-213 °C

Boiling Point

315.8°C at 760 mmHg

Density

1.3617 (estimate)

Flash Point

144.8℃

Refractive Index

1.6890 (rough estimate)

SMILES

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c1cc(c(c(c1)O)N)[N+](=O)[O-]

InChI

InChI=1S/C6H6N2O3/c7-6-4(8(10)11)2-1-3-5(6)9/h1-3,9H,7H2

InChIKey

KUCWUAFNGCMZDB-UHFFFAOYSA-N

LogP

1.98700

Complexity

156

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-Amino-3-nitrophenol
1-hydroxy-2-amino-3-nitrobenzene
2-amino-3-nitorophenol
2-amino-3-nitro-phenol
2-AMINO-3-NITROPHENOL PURUM,BROWN-RED
2-Hydroxy-6-nitroaniline
3-hydroxy-2-amino-nitrobenzene
3-Nitro-2-aminophenol
amino-nitro-phenol
EINECS 210-060-1
Phenol,2-amino-3-nitro
2-Amino-3-hydroxynitrobenzene

MDL Number

MFCD00010875

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 2-Amino-3-nitrophenol (CAS: 603-85-0)?

2-Amino-3-nitrophenol (CAS: 603-85-0) is a white crystalline solid with a molecular weight of 158.07 g/mol. It is slightly soluble in water and ethanol. Chemically, it is reactive towards acids, bases, and oxidizing agents. It has a pKa of approximately 9.7.

How is 2-Amino-3-nitrophenol (CAS: 603-85-0) typically synthesized?

2-Amino-3-nitrophenol (CAS: 603-85-0) is commonly synthesized by nitration of 2-aminophenol followed by purification. The reaction requires careful control of temperature and pH to achieve high selectivity and yield, often using sulfuric acid as a catalyst.

What industries use 2-Amino-3-nitrophenol (CAS: 603-85-0)?

2-Amino-3-nitrophenol (CAS: 603-85-0) is used in various industries, including pharmaceuticals, where it serves as an intermediate for the synthesis of certain drugs. It is also used in the production of dyes and pigments, as well as in environmental monitoring for the detection of pollutants.

What precautions should be taken when handling 2-Amino-3-nitrophenol (CAS: 603-85-0)?

When handling 2-Amino-3-nitrophenol (CAS: 603-85-0), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Always work in a well-ventilated area or a fume hood. Spills should be handled carefully using suitable absorbent materials and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed safety information.