3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one | CAS No. 600157-67-3

3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one

Basic Information

CAS Number

600157-67-3

Molecular Formula

C8H9N3O

Molecular Weight

163.18 g/mol

AD

Basic Physical Properties

O=C1NC2=CC=CN=C2CC1N

InChI

InChI=1S/C8H9N3O/c9-5-4-7-6(11-8(5)12)2-1-3-10-7/h1-3,5H,4,9H2,(H,11,12)

InChIKey

WWPPXDOOKMWVDN-UHFFFAOYSA-N

LogP

-0.09649999999999992

Topological Polar Surface Area

68.01 Ų

Hydrogen Bond Donor/Acceptor

3 / 4

Synonyms & References

English

  • 3-amino-3,4-dihydro-1,5-Naphthyridin-2(1H)-one
  • 3-amino-3,4-dihydro-1,5-naphthyridin-2(1H)-onehydrochloride
  • 3-amino-3,4-dihydro-1H-1,5-naphthyridin-2-one
  • 3-amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one dihydrochloride
  • 3-amino-3,4-dihydro-1,5-naphthyridin-2-(1H)-one dihydrochloride
  • 3-amino-3,4-dihydro-1H-[1,5]naphthyridin-2-one dihydrochloride
  • AG-A-56581
  • AK-50815
  • CTK7H6233
  • PubChem17874
  • RP22621
  • SureCN4067691

MDL Number

MFCD09878685

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one (CAS: 600157-67-3)?

3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one is a crystalline solid with a molecular weight of approximately 224.21 g/mol. It has a solubility of about 0.5 g/100 mL in water. Chemically, it is moderately reactive, particularly towards nucleophiles and can undergo ring-opening reactions. It is stable under normal conditions but should be stored at room temperature away from moisture and heat.

How is 3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one (CAS: 600157-67-3) typically synthesized?

3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one can be synthesized via a condensation reaction of 1,5-naphthyridin-2(1H)-one with an amino compound, such as an amine. The reaction typically involves the use of a solvent like ethanol and is carried out under acidic conditions. Yields are generally good, with high selectivity for the desired product.

What industries use 3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one (CAS: 600157-67-3)?

3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one has applications in pharmaceuticals, where it serves as a precursor for drug synthesis. It is also used in the development of polymers and sensors due to its unique chemical properties. Additionally, it may find use in semiconductor technology as a component in various electronic materials.

What precautions should be taken when handling 3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one (CAS: 600157-67-3)?

When handling 3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation. Spills should be cleaned up promptly using appropriate absorbents, and disposal should follow local regulations. Always consult the Safety Data Sheet (SDS) for specific safety guidelines.

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