3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one(CAS: 600157-67-3)

3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one is a crystalline solid with a molecular weight of approximately 224.21 g/mol. It has a solubility of about 0.5 g/100 mL in water. Chemically, it is moderately reactive, particularly towards nucleophiles and can undergo ring-opening reactions. It is stable under normal conditions but should be stored at room temperature away from moisture and heat.

3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one can be synthesized via a condensation reaction of 1,5-naphthyridin-2(1H)-one with an amino compound, such as an amine. The reaction typically involves the use of a solvent like ethanol and is carried out under acidic conditions. Yields are generally good, with high selectivity for the desired product.

3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one has applications in pharmaceuticals, where it serves as a precursor for drug synthesis. It is also used in the development of polymers and sensors due to its unique chemical properties. Additionally, it may find use in semiconductor technology as a component in various electronic materials.

When handling 3-Amino-3,4-dihydro-1,5-naphthyridin-2(1H)-one, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation. Spills should be cleaned up promptly using appropriate absorbents, and disposal should follow local regulations. Always consult the Safety Data Sheet (SDS) for specific safety guidelines.