(2R)-2-Octanol

Basic Information

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CAS Number

5978-70-1

Molecular Formula

C8H18O

Molecular Weight

130.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

-61.15°C (estimate)

Boiling Point

175 °C

Water Solubility

1 g/L (20 ºC)

Solubility

1g/l

Refractive Index

n20/D 1.426(lit.)

Specific Rotation

-9.5 º (neat)

SMILES

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CCCCCCC(C)O

InChI

InChI=1S/C8H18O/c1-3-4-5-6-7-8(2)9/h8-9H,3-7H2,1-2H3/t8-/m1/s1

InChIKey

SJWFXCIHNDVPSH-MRVPVSSYSA-N

LogP

2.3376

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

52.5

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H305 May be fatal if swallowed and enters airways
Aspiration hazard

H316 Causes mild skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H402 Harmful to aquatic life
Hazardous to the aquatic environment, acute hazard

Explosive Limit

0.8%(V)

Synonyms & References

English

5978-70-1
O0145
Q21546980
UNII-2SHB67XF6H
2-OCTANOL L-FORM [MI]
(R)-(-)-octan-2-ol
2-Octanol, (2R)-
2-Octanol, (R)-
2-Octanol #
DTXSID80884209
(R)-2-octanol
l-Octan-2-ol
L(-)-2-Octanol
2-OCTANOL, L-
L-(-)-OCTAN-2-OL
(2R)-octan-2-ol
(R)-(-)-Hexylmethylcarbinol
CHEBI:37871
AC1155
(R)-(-)-2-OCTYL ALCOHOL
(-)-2-OCTANOL
NS00125323
CS-0140572
(R)-Octan-2-ol
l-2-octanol
MFCD00064284
(R)-1-METHYLHEPTANOL
EINECS 227-777-0
LMFA05000547
r-(-)-2-octanol
2-OCTANOL L-FORM

MDL Number

MFCD00064284

Customs Code

29051620

FAQ

What are the physical and chemical properties of (2R)-2-Octanol (CAS: 5978-70-1)?

(2R)-2-Octanol is a colorless liquid with a characteristic odor. It has a molecular weight of 138.24 g/mol and a density of 0.811 g/cm³. The compound is slightly soluble in water but readily soluble in organic solvents like ethanol and chloroform. It is moderately reactive towards oxidizing agents and is used in various applications due to its functional group reactivity.

How is (2R)-2-Octanol (CAS: 5978-70-1) typically synthesized?

(2R)-2-Octanol can be synthesized via hydrogenation of 2-octanone using a catalyst such as palladium on carbon. The process typically yields 85-90% purity with good selectivity towards the (2R) isomer. Other methods include reduction of 2-octanone with sodium borohydride or lithium aluminum hydride, but these methods are less common and less selective.

What industries use (2R)-2-Octanol (CAS: 5978-70-1)?

(2R)-2-Octanol is widely used in the pharmaceutical, cosmetic, and fragrance industries. It is a key component in the formulation of perfumes and colognes due to its pleasant odor. In the pharmaceutical sector, it serves as a solvent for drug formulation and as a raw material for the synthesis of other compounds. Additionally, it finds applications in the polymer and sensor industries.

What precautions should be taken when handling (2R)-2-Octanol (CAS: 5978-70-1)?

When handling (2R)-2-Octanol, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up promptly using absorbent materials and appropriate waste disposal procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.