6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate

Basic Information

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CAS Number

595-33-5

Molecular Formula

C24H32O4

Molecular Weight

384.52 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

Powder

Melting Point

213.0 to 220.0 deg-C

Boiling Point

431.17°C (rough estimate)

Flash Point

218.5±30.2 °C

Refractive Index

1.551

Vapor Pressure

No data available

Specific Rotation

+9.0° to +13.0° (c=2, CHCl3)

SMILES

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CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C

InChI

InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1

InChIKey

RQZAXGRLVPAYTJ-GQFGMJRRSA-N

LogP

4.575300000000004

Topological Polar Surface Area

60.440000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

821

Safety Information

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GHS Hazard Pictograms

H351

Hazard Statement

H351 Suspected of causing cancer
Carcinogenicity

Synonyms & References

English

6-METHYL-3,20-DIOXOPREGNA-4,6-DIEN-17-YL ACETATE [WHO-IP]
Q-201346
Opera_ID_1511
SPBio_003101
RQZAXGRLVPAYTJ-GQFGMJRRSA-N
Ovaban Tablets 20 mg, Ovaban Tablets 5 mg
Megestrol acetate (USAN:USP)
CS-2065
NSC-71423
Megestat
Megestrol acetole
17-Hydroxy-6-methylpregna-4,20-dione acetate
MEGESTROL ACETATE (MART.)
SR-01000000258
SMR000058691
Megestrol acetate, European Pharmacopoeia (EP) Reference Standard
TJ2M0FR8ES
Megestol
Magestin
(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
HMS1570P14
MEGESTROL ACETATE (USP MONOGRAPH)
6-Dehydro-6-methyl-17-alpha-acetoxyprogesterone
HY-13676
MEGESTROL ACETATE (USP-RS)
NC00149
Megesterol acetate
Megestrol-17-acetate
MEGESTROL ACETATE [EP MONOGRAPH]
51154-23-5
17alpha-Acetoxy-6-methylpregna-4,6-diene-3,20-dione

MDL Number

MFCD00056470

FAQ

What is 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5)?

6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5) is a synthetic steroid derivative with the chemical formula C22H32O4. It is characterized by a pregnane core structure with methyl and acetyl groups, making it a progestogen compound. This compound is commonly used in pharmaceutical research for its hormonal activity and stability in organic solvents.

What are the main uses of 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5)?

6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5) is primarily utilized in pharmaceuticals as a progestin precursor and in drug synthesis. It also finds applications in research for studying steroid hormone mechanisms and in the development of contraceptive or anti-inflammatory agents. Industrial uses include its role as a chemical intermediate in organic synthesis processes.

Is 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5) safe?

6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5) is generally considered safe when handled properly, but it requires adherence to safety guidelines. Precautions include avoiding prolonged skin contact and inhalation, as it may cause irritation. Safety data sheets (SDS) recommend using appropriate PPE, and it is classified under controlled substance regulations for its pharmaceutical relevance.

How should 6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5) be stored?

6-Methyl-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 595-33-5) should be stored in a cool, dry place, away from light and moisture. Maintain storage temperature between 2-8°C and use airtight containers to prevent degradation. Avoid exposure to high humidity and ensure proper ventilation to maintain stability and safety during storage.