TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS | CAS No. 59481-23-1

TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS

Basic Information

CAS Number

59481-23-1

Molecular Formula

C82H108N18O20S2

Molecular Weight

1729.97 g/mol

AD

Basic Physical Properties

Density

1.44±0.1 g/cm3 (20 ºC 760 Torr),

CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(CC6=CC=C(C=C6)O)N)C(=O)O)CO)C(C)O)CC7=CC=CC=C7)O

InChI

InChI=1S/C82H108N18O20S2/c1-45(102)68-80(117)96-60(37-49-22-10-5-11-23-49)77(114)100-69(46(2)103)81(118)97-63(42-101)78(115)98-65(82(119)120)44-122-121-43-64(89-67(106)41-88-70(107)54(85)34-50-28-30-52(104)31-29-50)79(116)91-56(26-14-16-32-83)71(108)95-62(39-66(86)105)76(113)93-58(35-47-18-6-3-7-19-47)73(110)92-59(36-48-20-8-4-9-21-48)74(111)94-61(38-51-40-87-55-25-13-12-24-53(51)55)75(112)90-57(72(109)99-68)27-15-17-33-84/h3-13,18-25,28-31,40,45-46,54,56-65,68-69,87,101-104H,14-17,26-27,32-39,41-44,83-85H2,1-2H3,(H2,86,105)(H,88,107)(H,89,106)(H,90,112)(H,91,116)(H,92,110)(H,93,113)(H,94,111)(H,95,108)(H,96,117)(H,97,118)(H,98,115)(H,99,109)(H,100,114)(H,119,120)

InChIKey

HTAVEOUQMYLKNB-UHFFFAOYSA-N

LogP

-3.98520000000002

Topological Polar Surface Area

633.4599999999999 Ų

Hydrogen Bond Donor/Acceptor

27 / 38

Synonyms & References

English

  • H-TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH
  • H-TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14)
  • YGCKNFFWKTFTSC (DISULFIDE BRIDGE: 3-14)
  • [TYR1]-SOMATOSTATIN
  • (TYR1)-SOMATOSTATIN-14
  • [TYR1] SRIF
  • TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS
  • n-tyr(1)-somatostati
  • Somatostatin (sheep),1-L-tyrosine-
  • (Tyr?)-Somatostatin-14
  • [Tyr1]-Somatostatin
  • Tyr1]-Somatostatin[Tyr1]-Som
  • TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS(DISULFIDE BRIDGE: CYS3-CYS14)
  • TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS: YGCKNFFWKTFTSC DISULFIDE BRIDGE CYS3-CYS14

MDL Number

MFCD00076768

FAQ

What are the physical and chemical properties of TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS (CAS: 59481-23-1)?

This compound is a synthetic peptide with a molecular weight of approximately 1300 g/mol. It has a crystalline form and is slightly soluble in water. The peptide is reactive towards various functional groups and can participate in peptide coupling reactions.

How is TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS (CAS: 59481-23-1) typically synthesized?

This peptide is usually synthesized using solid-phase peptide synthesis (SPPS) methods. The process involves the use of Fmoc chemistry, where each amino acid is added sequentially to the growing peptide chain on a solid support. Commonly used catalysts include hydroxylamine or HATU. The yield is generally around 50-70%.

What industries use TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS (CAS: 59481-23-1)?

This peptide is used in the pharmaceutical industry for drug development and in the biotechnology field for protein engineering. It can also find applications in the polymer industry for developing smart materials and in the sensor industry for biosensing applications.

What precautions should be taken when handling TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS (CAS: 59481-23-1)?

When handling this compound, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and the material safety data sheet (MSDS) should be consulted for detailed emergency procedures.

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