Compound Q&A

How is TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS (CAS: 59481-23-1) typically synthesized?

Answer

TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS
This peptide is usually synthesized using solid-phase peptide synthesis (SPPS) methods. The process involves the use of Fmoc chemistry, where each amino acid is added sequentially to the growing peptide chain on a solid support. Commonly used catalysts include hydroxylamine or HATU. The yield is generally around 50-70%.

About

CAS No 59481-23-1
English Name TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS
Molecular Formula C82H108N18O20S2
Molecular Weight 1729.97 g/mol
SMILES CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(CC6=CC=C(C=C6)O)N)C(=O)O)CO)C(C)O)CC7=CC=CC=C7)O
InChIKey HTAVEOUQMYLKNB-UHFFFAOYSA-N
Last Updated: 2026-03-17 06:03

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