(2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (1:1) | CAS No. 58349-17-0

(2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (1:1)

Basic Information

CAS Number

58349-17-0

Molecular Formula

C11H16ClNO

Molecular Weight

213.71 g/mol

AD

Basic Physical Properties

Boiling Point

295.7°C at 760 mmHg

COC1=CC=CC2=C1CCC(C2)N.Cl

InChI

InChI=1S/C11H15NO.ClH/c1-13-11-4-2-3-8-7-9(12)5-6-10(8)11;/h2-4,9H,5-7,12H2,1H3;1H/t9-;/m0./s1

InChIKey

CGLCAQWQPIFKRX-FVGYRXGTSA-N

LogP

1.9330000000000003

Topological Polar Surface Area

35.25 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

172

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-, hydrochloride, (2S)-
  • CS-M1827
  • (S)-5-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
  • CGLCAQWQPIFKRX-FVGYRXGTSA-N
  • (S)-(-)-5-methoxy-2-aminotetraline hydrochloride
  • AKOS015914933
  • (S)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylamine hydrochloride
  • BCP12379
  • DTXSID30483988
  • AC-26363
  • (s)-2-amino-5-methoxytetralin hydrochloride
  • MFCD08443937
  • A24940
  • SCHEMBL3468007
  • 58349-17-0
  • PD016907
  • (2S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride
  • (S)-2-Amino-5-methoxytetraline hydrochloride
  • (S)-2-Amino-5-methoxytetrahydronaphthalene hydrochloride;(S)-2-Amino-5-methoxytetralin hydrochloride;4-tetrahydro-5-Methoxy-
  • (2S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
  • (2S)-5-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine--hydrogen chloride (1/1)
  • SS-4843
  • (S)-5-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine HCl
  • (S)-2-Amino-5-methoxytetrahydronaphthalene hydrochloride
  • (2S)-5-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
  • (RT-1) (S)-2-AMINO-5-METHOXYTETRALIN HYDROCHLORIDE
  • (S)-2-Ami-5-methoxytetralin Hydrochloride
  • (S)-2-Amino-5-methoxytetralin hydrochloride
  • 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-, hydrochloride (1:1), (2S)-
  • PubChem19174
  • 8642AB

MDL Number

MFCD08443937

Customs Code

2932999099

FAQ

What are the physical and chemical properties of (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0)?

The compound (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0) is a crystalline solid with a molecular weight of approximately 244.25 g/mol. It has a pKa of 3.0, indicating it is a weak acid. The compound is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. It reacts with bases to form the corresponding amine. It is stable under normal conditions but should be stored in a dry, cool place.

How is (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0) typically synthesized?

The compound (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0) is typically synthesized via the reduction of the corresponding naphthalenone derivative, followed by methylation and hydrolysis. The reaction involves the use of a reducing agent such as lithium aluminum hydride (LAH) and a methylation step using methyl iodide. The hydrochloride salt is then formed through acidification with hydrochloric acid.

What industries use (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0)?

The compound (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0) is used in various industries, including pharmaceuticals for developing certain types of drugs, and in the production of sensors and semiconductors. It can also be used in polymer synthesis as an intermediate or additive.

What precautions should be taken when handling (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0)?

When handling (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information and emergency procedures.

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