(2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (1:1)(CAS: 58349-17-0)

The compound (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0) is a crystalline solid with a molecular weight of approximately 244.25 g/mol. It has a pKa of 3.0, indicating it is a weak acid. The compound is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. It reacts with bases to form the corresponding amine. It is stable under normal conditions but should be stored in a dry, cool place.

The compound (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0) is typically synthesized via the reduction of the corresponding naphthalenone derivative, followed by methylation and hydrolysis. The reaction involves the use of a reducing agent such as lithium aluminum hydride (LAH) and a methylation step using methyl iodide. The hydrochloride salt is then formed through acidification with hydrochloric acid.

The compound (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0) is used in various industries, including pharmaceuticals for developing certain types of drugs, and in the production of sensors and semiconductors. It can also be used in polymer synthesis as an intermediate or additive.

When handling (2S)-5-Methoxy-1,2,3,4-tetrahydro-2-naphthalenamine hydrochloride (CAS: 58349-17-0), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information and emergency procedures.