6-Quinolinol | CAS No. 580-16-5

6-Quinolinol

Basic Information

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CAS Number

580-16-5

Molecular Formula

C9H7NO

Molecular Weight

145.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

188-190 °C

Boiling Point

264.27°C (rough estimate)

Flash Point

143.1℃

Refractive Index

1.4500 (estimate)

SMILES

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C1=CC2=C(C=CC(=C2)O)N=C1

InChI

InChI=1S/C9H7NO/c11-8-3-4-9-7(6-8)2-1-5-10-9/h1-6,11H

InChIKey

OVYWMEWYEJLIER-UHFFFAOYSA-N

LogP

1.9403999999999997

pKa

5.15, 8.90(at 20℃)

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

138

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A26208
6-Quinolinol, technical, >=95% (HPLC)
W-105418
6-Chinolinol
NSC-26343
BRN 0113196
Z759294450
6-HYDROXYQUINOLINE (6-QUINOLINOL)
BP-13160
NSC26343
AM20061342
InChI=1/C9H7NO/c11-8-3-4-9-7(6-8)2-1-5-10-9/h1-6,11H
CHEBI:48994
NSC 26343
6-Quinolinoloxine
6-hydroxy-quinoline
HYDROXYQUINOLINE, 6-
1H-1,6-Epoxyquinoline
UNII-95RU6I7UXL
Q0060
MFCD00047611
F0001-1515
6-hydroxy-chinolin
6-QUINOLINOL
CHEMBL1908053
CS-W007818
CX1058
SB67457
DTXSID40206726
Q27121428
CCRIS 4331

MDL Number

MFCD00047611

Customs Code

2933499090

FAQ

What regulatory guidelines apply to 6-Quinolinol (CAS: 580-16-5)?

6-Quinolinol (CAS: 580-16-5) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for hazardous properties such as skin irritation and potential carcinogenicity. In the European Union, it is also subject to the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) regulation. Additionally, the U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) may have specific requirements for its handling and disposal. Compliance with these regulations is essential to ensure safe and legal use of the compound.

Are there alternatives to 6-Quinolinol (CAS: 580-16-5) in synthesis?

Several alternatives to 6-Quinolinol (CAS: 580-16-5) can be used in synthesis, such as 8-Quinolinol or 7-Quinolinol, depending on the desired properties of the final product. Other potential alternatives include 6-Chloroquinoline or 6-Methylquinoline. These alternatives may offer different reactivity profiles and functional group compatibility, providing a range of options for synthetic chemists.

What is the market or research trend for 6-Quinolinol (CAS: 580-16-5)?

The market for 6-Quinolinol (CAS: 580-16-5) is driven by its applications in pharmaceuticals, particularly as a precursor for the synthesis of anticonvulsant and antipsychotic drugs. Research trends indicate a growing interest in its use as a ligand in transition metal catalysis for organometallic chemistry. Additionally, there is ongoing exploration of its use in dye and pigment synthesis, as well as in the development of new materials with electronic properties. The trend suggests a stable and potentially expanding market due to its versatile functionality.

How should waste containing 6-Quinolinol (CAS: 580-16-5) be handled?

Handling waste containing 6-Quinolinol (CAS: 580-16-5) requires careful consideration of its potential hazards. Waste should be collected in appropriate containers, labeled as hazardous, and stored in a well-ventilated area away from incompatible materials. For disposal, professional waste management services or incineration facilities with appropriate permits should be used. Environmental precautions include ensuring that waste does not enter water systems or soil, and that all personnel are trained in proper waste handling and disposal procedures to prevent exposure and contamination. Compliance with local, national, and international regulations is crucial for safe disposal.