2-Pyrazinecarbaldehyde

Basic Information

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CAS Number

5780-66-5

Molecular Formula

C5H4N2O

Molecular Weight

108.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

120-130°C

Density

1.234

Flash Point

70.5 °C

SMILES

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C1=CN=C(C=N1)C=O

InChI

InChI=1S/C5H4N2O/c8-4-5-3-6-1-2-7-5/h1-4H

InChIKey

DXBWJLDFSICTIH-UHFFFAOYSA-N

LogP

0.2890999999999999

Topological Polar Surface Area

42.85 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

84.5

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

FT-0600170
CS-W009118
MFCD02179278
2-FORMYLPYRAZINE
BDBM92858
5780-66-5
SCHEMBL3677331
2288709-85-1
AM20070428
AKOS012056702
PS-9298
J-524074
Z1013412214
DTXSID00460761
A831615
SCHEMBL193827
UNII-EX42FX5JBS
pyrazine-2-carbaldehyde, AldrichCPR
2-pyrazinecarboxaldehyde
SCHEMBL24025484
DXBWJLDFSICTIH-UHFFFAOYSA-N
PB19982
Pyrazine-2-carboxaldehyde
2-PYRAZINECARBALDEHYDE
SY023908
EN300-65142
PncA Inhibitor, 1
BB 0257252
formylpyrazine
Pyrazinecarboxaldehyde
Pyrazine-2-carbaldehyde

MDL Number

MFCD02179278

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Pyrazinecarbaldehyde (CAS: 5780-66-5)?

2-Pyrazinecarbaldehyde (CAS: 5780-66-5) is a crystalline solid with a molecular weight of approximately 123.11 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive, especially towards nucleophiles and reducing agents. It can undergo electrophilic aromatic substitution and condensation reactions.

How is 2-Pyrazinecarbaldehyde (CAS: 5780-66-5) typically synthesized?

2-Pyrazinecarbaldehyde (CAS: 5780-66-5) can be synthesized through the oxidation of pyrazine or by the condensation of a primary amine and a carboxylic acid. Common methods include using concentrated nitric acid or potassium permanganate as oxidants. The condensation method involves reacting an amine with formic acid in the presence of a catalyst such as p-toluenesulfonic acid.

What industries use 2-Pyrazinecarbaldehyde (CAS: 5780-66-5)?

2-Pyrazinecarbaldehyde (CAS: 5780-66-5) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the production of certain dyes and pigments, as well as in sensors for detecting various chemical and biological agents.

What precautions should be taken when handling 2-Pyrazinecarbaldehyde (CAS: 5780-66-5)?

When handling 2-Pyrazinecarbaldehyde (CAS: 5780-66-5), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure that the work is carried out in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the safety data sheet (SDS) for detailed handling and disposal information.