Compound Q&A

How is 2-Pyrazinecarbaldehyde (CAS: 5780-66-5) typically synthesized?

Answer

2-Pyrazinecarbaldehyde
2-Pyrazinecarbaldehyde (CAS: 5780-66-5) can be synthesized through the oxidation of pyrazine or by the condensation of a primary amine and a carboxylic acid. Common methods include using concentrated nitric acid or potassium permanganate as oxidants. The condensation method involves reacting an amine with formic acid in the presence of a catalyst such as p-toluenesulfonic acid.

About

CAS No 5780-66-5
English Name 2-Pyrazinecarbaldehyde
Molecular Formula C5H4N2O
Molecular Weight 108.1 g/mol
SMILES C1=CN=C(C=N1)C=O
InChIKey DXBWJLDFSICTIH-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21

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