Netilmicin sulfate

Basic Information

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CAS Number

56391-57-2

Molecular Formula

C21H43N5O11S

Molecular Weight

573.66 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

190-195°C

Boiling Point

684.3°C at 760 mmHg

Density

1.32

Water Solubility

Soluble in water

Flash Point

367.7 °C

Solubility

H2O: soluble10mg/mL

Specific Rotation

+88.0 - +96.0° (c=3, H2O)

SMILES

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OS(=O)(=O)O.CCN[C@@H]1C[C@H](N)[C@H]([C@@H]([C@H]1O[C@H]1OC[C@]([C@@H]([C@H]1O)NC)(C)O)O)O[C@H]1OC(=CC[C@H]1N)CN

InChI

InChI=1S/C21H41N5O7.H2O4S/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)14(27)17(13)33-20-15(28)18(25-3)21(2,29)9-30-20;1-5(2,3)4/h5,11-20,25-29H,4,6-9,22-24H2,1-3H3;(H2,1,2,3,4)/t11-,12+,13-,14+,15-,16-,17+,18-,19-,20-,21+;/m1./s1

InChIKey

PQHZSWZPVGHDEZ-UIQTUGNFSA-N

LogP

-3.8534999999999924

Topological Polar Surface Area

274.3299999999999 Å²

Hydrogen Bond Donor/Acceptor

13 / 16

Complexity

673

Safety Information

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GHS Hazard Pictograms

H360

Hazard Statement

H360 May damage fertility or the unborn child
Reproductive toxicity

Sensitiveness

Light Sensitive & Hygroscopic

Synonyms & References

English

Netilmicin sulfate
6-diamino-2,3,4,6-tetradeoxy-alpha-d-glycero-hex-4-enopyranosyl-(1-4)-6)-o-(
netromycin
sulfate(2:5)(salt)
(2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4-amino-3-[[(2s,3r)-3-amino-6-(aminomethyl)-3,4-dihydro-2h-pyran-2-yl]oxy]-6-ethylamino-2-hydroxycyclohexyl]oxy-5-methyl-4-methylaminooxane-3,5-diol sulfate (2:5)
1-N-ETHYLSISOMICIN
1-N-ETHYLSISOMICIN SULFATE
Netilmicin (sulfate)
NETILMICIN SULFATE, USP EP
0Netromycin,
Netilmicin sulfate salt
netilmicin
Netilmicinum
Netilmicine
Netilmicina
1-N-Aethylsisomicin
Netillin
Vectacin
Netilyn
Sch 20569
4O5J85GJJB
Netilmicin [INN:BAN]
Netilmicinum [INN-Latin]
Netilmicine [INN-French]
Netilmicina [INN-Spanish]
NTL
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4-amino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-(ethylamino)-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamin
SCH-20569 sulfate
1-N-Ethylsisomicin
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4-Amino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-ethylamino-2-hydroxycyclohexyl]oxy-5-methyl-4-methylaminooxane-3,5-diol sulfate (2:5)

MDL Number

MFCD26142629

Customs Code

2942000000

FAQ

What is Netilmicin sulfate (CAS: 56391-57-2)?

Netilmicin sulfate is an aminoglycoside antibiotic used to treat bacterial infections. It has the chemical formula C21H42N6O12S2 and is known for its broad-spectrum activity against both Gram-negative and Gram-positive bacteria. This compound is typically white to off-white in appearance and is highly soluble in water, making it suitable for pharmaceutical formulations.

What are the main uses of Netilmicin sulfate (CAS: 56391-57-2)?

Netilmicin sulfate is primarily used in the treatment of severe bacterial infections such as those affecting the respiratory tract, urinary system, and skin. It is also employed in veterinary medicine for livestock. As an antibiotic, it is commonly used in research settings to study bacterial resistance and in the development of new therapeutic agents.

Is Netilmicin sulfate (CAS: 56391-57-2) safe?

Netilmicin sulfate is generally considered safe when used as directed, but it can cause side effects such as nephrotoxicity and ototoxicity, especially with prolonged use. Proper handling and adherence to safety guidelines are essential. It is classified as a prescription medication and should be used under medical supervision to minimize risks and ensure appropriate therapeutic outcomes.

How should Netilmicin sulfate (CAS: 56391-57-2) be stored?

Netilmicin sulfate should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 15°C to 25°C (59°F to 77°F) and should be protected from moisture. The compound is usually stored in airtight containers to maintain its stability and prevent degradation over time.