Telavancin HCl | CAS No. 560130-42-9

Telavancin HCl

Basic Information

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CAS Number

560130-42-9

Molecular Formula

C80H107Cl3N11O27P

Molecular Weight

1792.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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ClC1C=C2[C@H]([C@H]3C(N[C@H](C(=O)O)C4C=C(C(CNCP(=O)(O)O)=C(C=4C4=C(C=CC(=C4)[C@H](C(N3)=O)NC([C@H]3C4=CC(=C(C(=C4)OC=1C=C2)O[C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O[C@H]1C[C@@](C)([C@@H]([C@H](C)O1)O)NCCNCCCCCCCCCC)OC1C=CC([C@H]([C@H](C(N[C@@H](CC(N)=O)C(N3)=O)=O)NC([C@@H](CC(C)C)NC)=O)O)=CC=1Cl)=O)O)O)O)=O)O.Cl

InChI

1S/C80H106Cl2N11O27P.ClH/c1-7-8-9-10-11-12-13-14-21-85-22-23-87-80(5)32-57(115-37(4)71(80)103)119-70-68(102)67(101)55(34-94)118-79(70)120-69-53-28-41-29-54(69)117-52-20-17-40(27-46(52)82)65(99)63-77(109)91-61(78(110)111)43-30-50(96)44(33-86-35-121(112,113)114)66(100)58(43)42-25-38(15-18-49(42)95)59(74(106)93-63)90-75(107)60(41)89-73(105)48(31-56(83)97)88-76(108)62(92-72(104)47(84-6)24-36(2)3)64(98)39-16-19-51(116-53)45(81)26-39;/h15-20,25-30,36-37,47-48,55,57,59-65,67-68,70-71,79,84-87,94-96,98-103H,7-14,21-24,31-35H2,1-6H3,(H2,83,97)(H,88,108)(H,89,105)(H,90,107)(H,91,109)(H,92,104)(H,93,106)(H,110,111)(H2,112,113,114);1H/t37-,47+,48-,55+,57-,59+,60+,61-,62+,63-,64+,65+,67+,68-,70+,71+,79-,80-;/m0./s1

InChIKey

GSSIWSIRBWAZHG-ACOPVEIWSA-N

LogP

3.1140000000000123

Topological Polar Surface Area

598.0899999999999 Å²

Hydrogen Bond Donor/Acceptor

24 / 38

Synonyms & References

English

Telavancin Hydrochloride
Td 6424
Td-6424
UNII-0701472ZG0
Vibativ
Vancomycin, N3'-(2-(decylamino)ethyl)-29-(((phosphonomethyl)amino)methyl)-, monohydrochloride
(3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-10,19-dichloro-44-((2-O-(3-((2-(decylamino)ethyl)amino)-3-C-methyl-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-7,22,28,30,32-pentahydroxy-6-(((2R)-4-methyl-2-(methylamino)pentanoyl)amino)-2,5,24,38,39-pentaoxo-29-(((phosphonomethyl)amino)methyl)-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-8,11:18,21-dietheno-23,36-(iminomethano)-22H-13,16:31,35-dime
(1S,2R,18S,19R,22S,25R,28R,40S)-22-(2-Amino-2-oxoethyl)-5,15-dichloro-48-[(2S,3R,4S,5S,6R)-3-[(2S,4S

MDL Number

MFCD22572780

FAQ

What is Telavancin HCl (CAS: 560130-42-9)?

Telavancin HCl is a semisynthetic lipoglycopeptide antibiotic. It is primarily known for its activity against Gram-positive bacteria, particularly those resistant to other antibiotics. Telavancin HCl has a unique chemical structure that includes a polyene skeleton with a hydroxyethylamine side chain, making it effective in treating various infections.

What are the main uses of Telavancin HCl (CAS: 560130-42-9)?

Telavancin HCl is mainly used in the treatment of hospital-acquired pneumonia and complicated skin and skin structure infections caused by sensitive bacteria. It is also utilized in the management of infections in patients with compromised immune systems or those with a history of antibiotic resistance.

Is Telavancin HCl (CAS: 560130-42-9) safe?

Telavancin HCl is considered generally safe when used under the guidance of a healthcare professional. However, it may cause side effects such as renal impairment, nausea, and vomiting. Patients should be monitored for these reactions and other potential adverse effects, and the drug should be used cautiously in individuals with renal dysfunction or those on other nephrotoxic medications.

How should Telavancin HCl (CAS: 560130-42-9) be stored?

Telavancin HCl should be stored at 2-8°C (36-46°F) in a refrigerator. It should be protected from light and kept in its original container. Avoid exposure to high temperatures and ensure that the container is tightly sealed to prevent the drug from degrading. It is recommended to use the drug within the expiration date indicated on the packaging to maintain its efficacy and safety.