6-Bromo-3-pyridinol

Basic Information

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CAS Number

55717-40-3

Molecular Formula

C5H4BrNO

Molecular Weight

174 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CC(=NC=C1O)Br

InChI

InChI=1S/C5H4BrNO/c6-5-2-1-4(8)3-7-5/h1-3,8H

InChIKey

PTEFNEALEPSHLC-UHFFFAOYSA-N

LogP

1.5496999999999999

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

78.8

Synonyms & References

English

FT-0660480
2-Bromo-5-hydroxypyridine, AldrichCPR
6-BROMO-PYRIDIN-3-OL
2-Bromo-5-hydroxypyridine
2-bromo-5-hydroxy-pyridine
B3657
CS-D0986
4-(3-THIEN-2-YL-1,2,4-OXADIAZOL-5-YL)BUTANOICACID
PS-5226
55717-45-8
AM20061326
5-Hydroxy-2-bromopyridine
Z1201622821
AKOS005146397
PB15771
J-518456
EN300-103371
2-bromo-5-hydroxy pyridine
A8044
A15649
6-Bromopyridin-3-ol
AC-25807
2-Bromo-5-hydroxypyridine radical ion(1+)
3-PYRIDINOL, 6-BROMO-
SCHEMBL148620
DTXSID80971087
SY003237
6-bromo-3-hydroxypyridine
CHEMBL3236917
6-Bromopyridin-3-ol (radical ion(1+))
3-hydroxy-6-bromopyridine

MDL Number

MFCD04114184

FAQ

What are the physical and chemical properties of 6-Bromo-3-pyridinol (CAS: 55717-40-3)?

6-Bromo-3-pyridinol (CAS: 55717-40-3) is a crystalline solid with a molecular weight of approximately 175.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents. It is prone to deamination under basic conditions.

How is 6-Bromo-3-pyridinol (CAS: 55717-40-3) typically synthesized?

6-Bromo-3-pyridinol is typically synthesized via the reduction of 6-bromo-3-pyridone using sodium borohydride. The reaction is usually carried out in anhydrous ethanol at room temperature, with high selectivity and yield. The process involves the addition of 6-bromo-3-pyridone to a stirred solution of sodium borohydride in ethanol, followed by purification using recrystallization.

What industries use 6-Bromo-3-pyridinol (CAS: 55717-40-3)?

6-Bromo-3-pyridinol is primarily used in the pharmaceutical industry as an intermediate in drug synthesis. It also finds applications in the polymer industry for the development of functional materials and in the electronic industry for the production of sensors and semiconductors.

What precautions should be taken when handling 6-Bromo-3-pyridinol (CAS: 55717-40-3)?

When handling 6-Bromo-3-pyridinol (CAS: 55717-40-3), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to avoid prolonged exposure to the fumes. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.