6-Bromo-3-pyridinol(CAS: 55717-40-3)

6-Bromo-3-pyridinol (CAS: 55717-40-3) is a crystalline solid with a molecular weight of approximately 175.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents. It is prone to deamination under basic conditions.

6-Bromo-3-pyridinol is typically synthesized via the reduction of 6-bromo-3-pyridone using sodium borohydride. The reaction is usually carried out in anhydrous ethanol at room temperature, with high selectivity and yield. The process involves the addition of 6-bromo-3-pyridone to a stirred solution of sodium borohydride in ethanol, followed by purification using recrystallization.

6-Bromo-3-pyridinol is primarily used in the pharmaceutical industry as an intermediate in drug synthesis. It also finds applications in the polymer industry for the development of functional materials and in the electronic industry for the production of sensors and semiconductors.

When handling 6-Bromo-3-pyridinol (CAS: 55717-40-3), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to avoid prolonged exposure to the fumes. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.