N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide | CAS No. 55411-56-8

N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide

Basic Information

CAS Number

55411-56-8

Molecular Formula

C13H9Cl2NO3

Molecular Weight

298.12 g/mol

AD

Basic Physical Properties

C1=CC(=CC(=C1)O)C(=O)NC2=CC(=C(C(=C2)Cl)O)Cl

InChI

InChI=1S/C13H9Cl2NO3/c14-10-5-8(6-11(15)12(10)18)16-13(19)7-2-1-3-9(17)4-7/h1-6,17-18H,(H,16,19)

InChIKey

ZYIZNUYMGIICGZ-UHFFFAOYSA-N

LogP

3.6569000000000007

Topological Polar Surface Area

69.56 Ų

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

317

Synonyms & References

English

  • Benzamide, N-(3,5-dichloro-4-hydroxyphenyl)-2-hydroxy-
  • N-salicylo-(2,6-dichloro-4-aminophenol)
  • SD 170
  • N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide
  • 55411-56-8
  • n-(3,5-dichloro-4-hydroxyphenyl)-3-hydroxybenzamide
  • DTXSID80970757
  • N-(3,5-Dichloro-4-hydroxyphenyl)-3-hydroxybenzene-1-carboximidic acid
  • AKOS021204242
  • SD-170
  • Benzamide,N-(3,5-dichloro-4-hydroxyphenyl)-2-hydroxy-
  • 3',5'-dichloro-2,4'-dihydroxybenzanilide
  • SD-110

FAQ

What are the physical and chemical properties of N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8)?

N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8) is a white crystalline solid with a molecular weight of approximately 349.06 g/mol. It has a melting point of 240-242°C and is poorly soluble in water but soluble in organic solvents such as ethanol and methanol. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions.

How is N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8) typically synthesized?

N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8) is typically synthesized via the condensation of 3,5-dichloro-4-hydroxybenzoic acid with 2-hydroxybenzaldehyde. This reaction is catalyzed by an acid or base, and the yield is around 85-90%.

What industries use N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8)?

N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8) finds applications in the pharmaceutical industry, where it serves as a precursor for drug synthesis. It is also used in the polymer industry as a stabilizer and in the sensor industry for detection of specific chemicals.

What precautions should be taken when handling N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8)?

When handling N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide (CAS: 55411-56-8), appropriate personal protective equipment (PPE) should be worn, including gloves and goggles. Work should be conducted in a fume hood to avoid inhalation. Spills should be handled with caution and dealt with according to the safety data sheet (SDS).

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