Triamcinolone Acetonide Impurity 3

Basic Information

View in Editor

CAS Number

5541-37-7

Molecular Formula

C24H30O5

Molecular Weight

398.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

Off-White to Pale Beige

Melting Point

>200°C (dec.)

Solubility

Chloroform (Slightly), Methanol (Slightly)

SMILES

View in Editor

CC1(C)O[C@@H]2CC3C4CCC5=CC(=O)C=C[C@]5(C)C4=CC[C@]3(C)[C@@]2(O1)C(=O)CO

InChI

InChI=1S/C24H30O5/c1-21(2)28-20-12-18-16-6-5-14-11-15(26)7-9-22(14,3)17(16)8-10-23(18,4)24(20,29-21)19(27)13-25/h7-9,11,16,18,20,25H,5-6,10,12-13H2,1-4H3/t16?,18?,20-,22+,23+,24-/m1/s1

InChIKey

XTAIWNCAVBJJDD-OQYXIQFSSA-N

LogP

3.276000000000003

Topological Polar Surface Area

72.83 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

895

Synonyms & References

English

Desonide delta 9 (11) analog
9-Desfluoro-11-dehydroxy-9(11)-ene Triamcinolone Acetonide
(16α)-21-Hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4,9(11)-triene-3,20-dione
TCA Impurity D
Budenoside Impurity 12
Desonide Anhydro Impurity
Pregna-1,4,9(11)-triene-3,20-dione, 21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (16α)-
Diolone Acetonide
9,11-Dehydro Triamcinolone Acetonide
CID 145714568
(6aS,8aS,8bS,11aR,12aS,12bS)-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,8,8a,8b,11a,12,12a,12b-decahydro-4H-naphtho [2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
(6aS,8aS,8bS,11aR,12aS,12bS)-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,8,8a,8b,11a,12,12a,12b-decahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

MDL Number

MFCD28359070

FAQ

What are the physical and chemical properties of Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7)?

Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7) is a white to off-white crystalline powder. It has a molecular weight of approximately 532.63 g/mol. This impurity is slightly soluble in water and ethanol. It is not highly reactive under normal conditions but may undergo hydrolysis in the presence of water or acids. It is insoluble in common organic solvents such as chloroform and ether.

How is Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7) typically synthesized?

Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7) is synthesized through a series of reactions starting from triamcinolone acetonide. Commonly, it involves hydrogenation, oxidation, and/or reduction steps. The exact methodology can vary depending on the desired purity and yield, but typically, the synthesis involves the use of catalysts like palladium on carbon and various oxidants or reductants to achieve the desired impurity profile.

What industries use Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7)?

Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7) is primarily used in the pharmaceutical industry as an impurity in the synthesis of triamcinolone acetonide. It is also relevant in the research and development of other steroid compounds. Its use in other industries such as polymers, sensors, and semiconductors is minimal due to its limited reactivity and specific applications.

What precautions should be taken when handling Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7)?

When handling Triamcinolone Acetonide Impurity 3 (CAS: 5541-37-7), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be carefully cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.