3-Amino-2-thiophenecarboxylic acid

Basic Information

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CAS Number

55341-87-2

Molecular Formula

C5H5NO2S

Molecular Weight

143.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

399 ℃ at 760 mmHg

Density

1.527

Flash Point

195.1℃

Refractive Index

1.689

SMILES

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C1=CSC(=C1N)C(=O)O

InChI

InChI=1S/C5H5NO2S/c6-3-1-2-9-4(3)5(7)8/h1-2H,6H2,(H,7,8)

InChIKey

CQSJDKGNONPQOQ-UHFFFAOYSA-N

LogP

1.0285

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

128

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

aminothiophenecarboxylic
SY006053
55341-87-2
CQSJDKGNONPQOQ-UHFFFAOYSA-N
J-511739
SCHEMBL930387
DTXSID20363689
3-amino-thiophene-2-carboxylic acid
AKOS005174251
3-Amino-2-thiophenecarboxylicAcid
CS-0059259
AC-24323
A830600
3-Amino-2-thiophenecarboxylic acid
3-aminothiophene-2-carboxylic
FT-0659037
3-aminothiophene-2-carboxylic Acid
2-THIOPHENECARBOXYLIC ACID, 3-AMINO-
EN300-99433
POTASSIUM 3-AMINOTHIOPHENE-2-CARBOXYLIC ACID
MFCD03426100
3-Aminothiophene-2-carboxylic acid
3-AMINO-2-THIOPHENECARBOXYLIC ACID POTASSIUM SALT
3-aminothiophene-2-carboxylic acid

MDL Number

MFCD03426100

FAQ

What are the physical and chemical properties of 3-Amino-2-thiophenecarboxylic acid (CAS: 55341-87-2)?

3-Amino-2-thiophenecarboxylic acid is a white crystalline solid with a molecular weight of approximately 169.21 g/mol. It has a solubility of 2.7 g/L in water at 25°C. Chemically, it shows basic properties due to the amino group and is reactive towards acid and base catalyzed reactions.

How is 3-Amino-2-thiophenecarboxylic acid (CAS: 55341-87-2) typically synthesized?

3-Amino-2-thiophenecarboxylic acid is usually synthesized via the condensation of thiophene-2-carboxylic acid with ammonia. Commonly, this reaction is carried out in an acidic medium, with reagents like glacial acetic acid. The yield can be up to 80%, and the method is selective and efficient.

What industries use 3-Amino-2-thiophenecarboxylic acid (CAS: 55341-87-2)?

3-Amino-2-thiophenecarboxylic acid is utilized in various industries including pharmaceuticals for the synthesis of drug intermediates, and in the polymer industry for functionalizing polymers. It is also used in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 3-Amino-2-thiophenecarboxylic acid (CAS: 55341-87-2)?

When handling 3-Amino-2-thiophenecarboxylic acid, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled by neutralizing with acid or base, followed by thorough cleaning. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.