3-Amino-2-thiophenecarboxylic acid(CAS: 55341-87-2)

3-Amino-2-thiophenecarboxylic acid is a white crystalline solid with a molecular weight of approximately 169.21 g/mol. It has a solubility of 2.7 g/L in water at 25°C. Chemically, it shows basic properties due to the amino group and is reactive towards acid and base catalyzed reactions.

3-Amino-2-thiophenecarboxylic acid is usually synthesized via the condensation of thiophene-2-carboxylic acid with ammonia. Commonly, this reaction is carried out in an acidic medium, with reagents like glacial acetic acid. The yield can be up to 80%, and the method is selective and efficient.

3-Amino-2-thiophenecarboxylic acid is utilized in various industries including pharmaceuticals for the synthesis of drug intermediates, and in the polymer industry for functionalizing polymers. It is also used in the development of sensors and semiconductors due to its unique chemical properties.

When handling 3-Amino-2-thiophenecarboxylic acid, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled by neutralizing with acid or base, followed by thorough cleaning. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.