5-Amino-2-pyridinecarbonitrile

Basic Information

View in Editor

CAS Number

55338-73-3

Molecular Formula

C6H5N3

Molecular Weight

119.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Solid

Melting Point

148-152 °C

Boiling Point

368.2 °C at 760 mmHg

Density

1.23

Flash Point

176.5 °C

Refractive Index

1.594

SMILES

View in Editor

C1=CC(=NC=C1N)C#N

InChI

InChI=1S/C6H5N3/c7-3-6-2-1-5(8)4-9-6/h1-2,4H,8H2

InChIKey

IFOXWHQFTSCNQB-UHFFFAOYSA-N

LogP

1.11668

pKa

0.61±0.10(Predicted)

Complexity

135

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Storage Conditions

Keep in dark place,Inert atmosphere,Room temperature

Synonyms & References

English

FT-0640303
Z1065674734
5-Amino-2-cyanopyridine
A8016
55338-73-3
AKOS005137887
BCP26820
5-Amino-2-pyridinecarbonitrile, 96%
5-aminopyridine-2-carbonitrile
CS-W016585
J-511672
2-cyano-5-aminopyridine
AC-6595
EN300-66901
5-amino-2-cyano pyridine
SCHEMBL42349
5-aminopicolinonitrile
5-Amino-2-cyanopyridine pound>>3-Amino-6-cyanopyridine
BP-10408
IFOXWHQFTSCNQB-UHFFFAOYSA-N
SY020835
2-Pyridinecarbonitrile, 5-amino-
MFCD03093956
PB14307
5-Amino-2-pyridinecarbonitrile
DTXSID30397657
3-Amino-6-cyanopyridine
AM1075
TS-01610
5-Amino-2-cyano-pyridine
5-amino-pyridine-2-carbonitrile

MDL Number

MFCD03093956

Customs Code

2933399990

FAQ

What are the physical and chemical properties of 5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3)?

5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3) is a crystalline solid with a molecular weight of approximately 145.17 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetonitrile. The compound is relatively stable but can react with strong acids or bases. It does not have significant reactivity under normal conditions but may undergo substitution reactions under certain conditions.

How is 5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3) typically synthesized?

5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3) is typically synthesized via a multistep process that starts with the nitrile group attachment to the pyridine ring. A common method involves the reaction of 2-chloro-5-nitropyridine with sodium cyanide in the presence of a base like sodium hydroxide. The product is then converted to the amino derivative by reducing the nitro group to an amino group.

What industries use 5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3)?

5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3) is used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It also finds applications in the polymer industry for modifying properties of polymers. Additionally, it is used in the development of sensors and as a precursor in the semiconductor industry for electronic applications.

What precautions should be taken when handling 5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3)?

When handling 5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate materials and using proper disposal methods. Always refer to the Safety Data Sheet (SDS) for specific handling and storage guidelines.