Compound Q&A

How is 5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3) typically synthesized?

Answer

5-Amino-2-pyridinecarbonitrile
5-Amino-2-pyridinecarbonitrile (CAS: 55338-73-3) is typically synthesized via a multistep process that starts with the nitrile group attachment to the pyridine ring. A common method involves the reaction of 2-chloro-5-nitropyridine with sodium cyanide in the presence of a base like sodium hydroxide. The product is then converted to the amino derivative by reducing the nitro group to an amino group.

About

CAS No 55338-73-3
English Name 5-Amino-2-pyridinecarbonitrile
Molecular Formula C6H5N3
Molecular Weight 119.12 g/mol
SMILES C1=CC(=NC=C1N)C#N
InChIKey IFOXWHQFTSCNQB-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55

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