Cloprostenol sodium

Basic Information

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CAS Number

55028-72-3

Molecular Formula

C22H28ClNaO6

Molecular Weight

446.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

68-70 ºC

Boiling Point

628°C at 760 mmHg

Solubility

H2O: >10 mg/mL

SMILES

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C1C(C(C(C1O)C=CC(COC2=CC(=CC=C2)Cl)O)CC=CCCCC(=O)[O-])O.[Na+]

InChI

InChI=1S/C22H29ClO6.Na/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28;/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28);/q;+1/p-1/b3-1-,11-10+;/t16-,18-,19-,20+,21-;/m1./s1

InChIKey

IFEJLMHZNQJGQU-KXXGZHCCSA-M

LogP

1.86030

Complexity

558

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

5-Heptenoic acid, 7-((1R,2R,3R,5S)-2-((1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl)-3,5-dihydroxycyclopentyl)-, monosodium salt, (5Z)-rel-
A850969
CLOPROSTENOL SODIUM (USP MONOGRAPH)
EINECS 259-439-3
(+)-Cloprostenol sodium
16-(m-Chlorophenoxy)-tetranor- prostaglandin F2alpha,sodium salt
Sodium, Cloprostenol
HMS1361O21
(+/-)-Cloprostenol sodium salt
(+)-Cloprostenol (sodium salt)
Sodium (Z)-rel-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate
(+)-16-m-chlorophenoxy tetranor PGF2alpha
AC-6102
AT39750
HMS3413C18
SCHEMBL28242
81129I41BJ
(5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid monosodium salt
5-HEPTENOIC ACID, 7-(2-(4-(3-CHLOROPHENOXY)-3-HYDROXY-1-BUTENYL)-3,5-DIHYDROXYCYCLOPENTYL)-, (1A(Z),2B(1E,3R*),3alpha,5alpha)-, SODIUM SALT, (+/-)-
(+/-)-SODIUM (Z)-7-((1R*,2R*,3R*,5S*)-2-((E)-(3R*)-4-(M-CHLOROPHENOXY)-3-HYDROXY-1-BUTENYL)-3,5-DIHYDROXYCYCLOPENTYL)-5-HEPTENOATE
UNII-81129I41BJ
Sodium;(Z)-7-[(1S,2S,3S,5R)-2-[(E,3S)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoate
CHEMBL1520583
Sodium(Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate
CLOPROSTENOL SODIUM [GREEN BOOK]
J-524247
Sodium (Z)-7-((1R,2R,3R,5S)-2-((R,E)-4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enoate
SYNCHSURE
CLOPROSTENOL SODIUM (USP-RS)
(5Z)-rel-Cloprostenol Sodium
EX-A1351

MDL Number

MFCD11045985

FAQ

What are the physical and chemical properties of Cloprostenol sodium (CAS: 55028-72-3)?

Cloprostenol sodium (CAS: 55028-72-3) is a white to off-white crystalline powder. It has a molecular weight of approximately 372.46 g/mol. It is sparingly soluble in water and ethanol. It is stable under normal conditions but should be stored away from high temperatures and direct sunlight. It is known to be a potent progestin and has limited reactivity under normal conditions.

How is Cloprostenol sodium (CAS: 55028-72-3) typically synthesized?

Cloprostenol sodium is typically synthesized from cloprostenol by adding sodium hydroxide. The reaction involves the base-catalyzed condensation of cloprostenol with sodium hydroxide, leading to the formation of sodium salts. The process requires attention to pH control and temperature to ensure high yield and selectivity. The reaction is usually carried out in a well-ventilated area and protective equipment should be used.

What industries use Cloprostenol sodium (CAS: 55028-72-3)?

Cloprostenol sodium (CAS: 55028-72-3) is primarily used in the pharmaceutical industry as a veterinary drug for inducing estrus in cattle. It is also used in the agricultural sector for controlling estrus synchronization in animals. While it has limited applications in other industries, it plays a significant role in the aforementioned fields.

What precautions should be taken when handling Cloprostenol sodium (CAS: 55028-72-3)?

When handling Cloprostenol sodium (CAS: 55028-72-3), it is important to use personal protective equipment (PPE) such as gloves and safety goggles. The substance should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up using absorbent material and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and safety measures.