6-Chloro-N-methylnicotinamide

Basic Information

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CAS Number

54189-82-1

Molecular Formula

C7H7ClN2O

Molecular Weight

170.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CNC(=O)C1=CN=C(C=C1)Cl

InChI

InChI=1S/C7H7ClN2O/c1-9-7(11)5-2-3-6(8)10-4-5/h2-4H,1H3,(H,9,11)

InChIKey

DEYOMDZKXMQLCF-UHFFFAOYSA-N

LogP

1.0946

Topological Polar Surface Area

41.99 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

151

Synonyms & References

English

54189-82-1
MFCD08460991
AKOS000200516
DTXSID30494337
3-Pyridinecarboxamide, 6-chloro-N-methyl-
CS-W006347
A870525
Z32016558
DEYOMDZKXMQLCF-UHFFFAOYSA-N
6-chloro-N-methylnicotinamide
EN300-29384
6-Chloro-N-methyl-nicotinamide
SCHEMBL103123
AS-8415
6-chloro-N-methylpyridine-3-carboxamide
6-chloro-nicotinic acid N-methylamide
SY107933
N11734
6-chloro-N-methyl-3-pyridinecarboxamide
2-Chloro-5-(methylaminocarbonyl)pyridine
6-Chloro-N-methylnicotinamide
3-Pyridinecarboxamide,6-chloro-N-methyl-
2-chloro-5-(methylaminocarbonyl)pyridine
6-chloro-N-methylnicotinacidamide
6-chloro-N-methyl-pyridine-3-carboxamide
5281AE
N-Methyl-6-chloropyridine-3-carboxamide

MDL Number

MFCD08460991

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Chloro-N-methylnicotinamide (CAS: 54189-82-1)?

6-Chloro-N-methylnicotinamide (CAS: 54189-82-1) is a crystalline solid with a molecular weight of approximately 173.61 g/mol. It is slightly soluble in water and ethanol. Chemically, it is a derivative of nicotinamide with a chlorine atom and a methyl group substitution. It is stable under normal conditions but reacts with strong bases and reducing agents.

How is 6-Chloro-N-methylnicotinamide (CAS: 54189-82-1) typically synthesized?

6-Chloro-N-methylnicotinamide is typically synthesized from nicotinamide via chloromethylation. The process involves treating nicotinamide with methyl chloride in the presence of a suitable catalyst, such as aluminum chloride, to produce the desired compound with high selectivity and yield.

What industries use 6-Chloro-N-methylnicotinamide (CAS: 54189-82-1)?

6-Chloro-N-methylnicotinamide (CAS: 54189-82-1) is used in the pharmaceutical industry for its potential in drug development, particularly in treatments related to metabolic disorders and neurodegenerative diseases. It also finds applications in the research and development of new materials in the polymer and semiconductor industries.

What precautions should be taken when handling 6-Chloro-N-methylnicotinamide (CAS: 54189-82-1)?

When handling 6-Chloro-N-methylnicotinamide (CAS: 54189-82-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate materials, and proper disposal methods should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.