6-Chloro-N-methylnicotinamide(CAS: 54189-82-1)

6-Chloro-N-methylnicotinamide (CAS: 54189-82-1) is a crystalline solid with a molecular weight of approximately 173.61 g/mol. It is slightly soluble in water and ethanol. Chemically, it is a derivative of nicotinamide with a chlorine atom and a methyl group substitution. It is stable under normal conditions but reacts with strong bases and reducing agents.

6-Chloro-N-methylnicotinamide is typically synthesized from nicotinamide via chloromethylation. The process involves treating nicotinamide with methyl chloride in the presence of a suitable catalyst, such as aluminum chloride, to produce the desired compound with high selectivity and yield.

6-Chloro-N-methylnicotinamide (CAS: 54189-82-1) is used in the pharmaceutical industry for its potential in drug development, particularly in treatments related to metabolic disorders and neurodegenerative diseases. It also finds applications in the research and development of new materials in the polymer and semiconductor industries.

When handling 6-Chloro-N-methylnicotinamide (CAS: 54189-82-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate materials, and proper disposal methods should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.