4-(Tetrahydro-2H-pyran-2-yloxy)phenol

Basic Information

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CAS Number

53936-56-4

Molecular Formula

C11H14O3

Molecular Weight

194.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Boiling Point

349.8°C at 760 mmHg

Density

1.174

SMILES

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OC1=CC=C(OC2CCCCO2)C=C1

InChI

InChI=1S/C11H14O3/c12-9-4-6-10(7-5-9)14-11-3-1-2-8-13-11/h4-7,11-12H,1-3,8H2

InChIKey

GFBCWCDNXDKFRH-UHFFFAOYSA-N

LogP

2.2976

Topological Polar Surface Area

38.69 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

164

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-((Tetrahydro-2H-pyran-2-yl)oxy)phenol
Deoxyarbutin
Phenol,4-[(tetrahydro-2H-pyran-2-yl)oxy]-
4-(oxan-2-yloxy)phenol
4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol
Phenol (4-[(tetrahydro-2H-pyran-2-yl)oxy]
Phenol, 4-[(tetrahydro-2H-pyran-2-yl)oxy]-
4-(Tetrahydro-2H-pyran-2-yloxy)phenol
4-((2-Tetrahydropyranyl)oxy)phenol
Phenol, 4-((tetrahydro-2H-pyran-2-yl)oxy)-
4-[(2-Tetrahydropyranyl)oxy]phenol
Girlite DA 100
Tetrahydropyranyloxy phenol
D-arbutin
(+/-)-Tetrahydropyranyloxy phenol
Tetrahydropyranyloxy phenol [INCI]
Tetrahydropyranyloxy phenol, (+/-)-
4-Hydroxyphenyl tetrahydropyranyl ether
4-[(Oxan-2-yl)oxy]phe

MDL Number

MFCD09970981

Customs Code

2938909090

FAQ

What is 4-(Tetrahydro-2H-pyran-2-yloxy)phenol (CAS: 53936-56-4)?

4-(Tetrahydro-2H-pyran-2-yloxy)phenol is an organic compound with the chemical formula C9H10O3. It is a phenolic ether characterized by its hydroxyphenyl group connected to a tetrahydrofuran ring. This compound is commonly used as an intermediate in pharmaceutical and chemical synthesis due to its reactivity and structural versatility. Its physical properties include solubility in organic solvents and a characteristic mild aromatic odor.

What are the main uses of 4-(Tetrahydro-2H-pyran-2-yloxy)phenol (CAS: 53936-56-4)?

4-(Tetrahydro-2H-pyran-2-yloxy)phenol finds applications in pharmaceutical research as a building block for drug development, particularly in compounds targeting anti-inflammatory or analgesic properties. It is also used in industrial processes for polymer synthesis and as a stabilizer in organic formulations. In food chemistry, it may serve as a flavor enhancer, while in research, it is employed for studying ether functional group reactivity and catalytic mechanisms.

Is 4-(Tetrahydro-2H-pyran-2-yloxy)phenol (CAS: 53936-56-4) safe?

4-(Tetrahydro-2H-pyran-2-yloxy)phenol is generally considered safe when handled properly, but it may cause mild skin or eye irritation. Safety precautions include using personal protective equipment (PPE) like gloves and goggles, and working in a well-ventilated area. It is non-flammable but should comply with standard chemical safety guidelines, such as those outlined in OSHA and SDS, to ensure safe handling and exposure limits.

How should 4-(Tetrahydro-2H-pyran-2-yloxy)phenol (CAS: 53936-56-4) be stored?

Store 4-(Tetrahydro-2H-pyran-2-yloxy)phenol in a sealed, airtight container at room temperature (15-25°C) in a cool, dry place away from light. Maintain low humidity to prevent hydrolysis, and ensure it is kept separate from incompatible materials. Stability is optimal under these conditions, but always follow safety protocols to avoid degradation or contamination.