4-(Tetrahydro-2H-pyran-2-yloxy)phenol(CAS: 53936-56-4)

4-(Tetrahydro-2H-pyran-2-yloxy)phenol is an organic compound with the chemical formula C9H10O3. It is a phenolic ether characterized by its hydroxyphenyl group connected to a tetrahydrofuran ring. This compound is commonly used as an intermediate in pharmaceutical and chemical synthesis due to its reactivity and structural versatility. Its physical properties include solubility in organic solvents and a characteristic mild aromatic odor.

4-(Tetrahydro-2H-pyran-2-yloxy)phenol finds applications in pharmaceutical research as a building block for drug development, particularly in compounds targeting anti-inflammatory or analgesic properties. It is also used in industrial processes for polymer synthesis and as a stabilizer in organic formulations. In food chemistry, it may serve as a flavor enhancer, while in research, it is employed for studying ether functional group reactivity and catalytic mechanisms.

4-(Tetrahydro-2H-pyran-2-yloxy)phenol is generally considered safe when handled properly, but it may cause mild skin or eye irritation. Safety precautions include using personal protective equipment (PPE) like gloves and goggles, and working in a well-ventilated area. It is non-flammable but should comply with standard chemical safety guidelines, such as those outlined in OSHA and SDS, to ensure safe handling and exposure limits.

Store 4-(Tetrahydro-2H-pyran-2-yloxy)phenol in a sealed, airtight container at room temperature (15-25°C) in a cool, dry place away from light. Maintain low humidity to prevent hydrolysis, and ensure it is kept separate from incompatible materials. Stability is optimal under these conditions, but always follow safety protocols to avoid degradation or contamination.