Apixaban Impurity 47

Basic Information

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CAS Number

536759-91-8

Molecular Formula

C22H20N4O6

Molecular Weight

436.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

658.8°C at 760 mmHg

Density

1.40

SMILES

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O=C(C1=NN(C2=CC=C(OC)C=C2)C3=C1CCN(C4=CC=C([N+]([O-])=O)C=C4)C3=O)OCC

InChI

InChI=1S/C22H20N4O6/c1-3-32-22(28)19-18-12-13-24(14-4-6-16(7-5-14)26(29)30)21(27)20(18)25(23-19)15-8-10-17(31-2)11-9-15/h4-11H,3,12-13H2,1-2H3

InChIKey

RQNAOIQEGPVYTC-UHFFFAOYSA-N

LogP

3.75690

Complexity

699

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
4,5,6,7-Tetrahydro-1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxyl
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3
1H-Pyrazolo[3,4-c]pyridine-3-carboxylicacid,4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-,ethylester
Apixaban iMpurityG
Apixaban impurity BMS-589154
4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl este
4-5-6-7-Tetrahydro-1--4-methoxyphenyl--6--4-nitrophenyl--7-oxo-1H-pyrazolo-3-4-c-pyridine-3-ca...
4-5-6-7-Tetrahydro-1--4-methoxyphenyl--6--4-nitrophenyl--7-oxo-1H-pyrazolo-3-4-c-pyridine-3-carboxylic-acid-ethyl-ester
ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
Ethyl1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
RQNAOIQEGPVYTC-UHFFFAOYSA-N
CID 11711790
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-ca
Ethyl1-(4-Methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-t

MDL Number

MFCD18251627

FAQ

What is Apixaban Impurity 47 (CAS: 536759-91-8)?

Apixaban Impurity 47 is a specific chemical compound identified by the CAS number 536759-91-8. It is an impurity associated with apixaban, an anticoagulant drug used in pharmaceuticals. The compound typically exhibits structural similarity to apixaban and is characterized by its chemical properties relevant to drug purity analysis.

What are the main uses of Apixaban Impurity 47 (CAS: 536759-91-8)?

Apixaban Impurity 47 is primarily used in pharmaceutical research and quality control to identify and quantify impurities in apixaban production. It also serves as a reference standard in drug testing, ensuring compliance with regulatory requirements for drug safety and efficacy.

Is Apixaban Impurity 47 (CAS: 536759-91-8) safe?

Apixaban Impurity 47 is generally considered safe in controlled laboratory settings and at low concentrations. However, standard safety precautions should be followed, including wearing gloves and ensuring proper ventilation. Its safety profile is evaluated under regulatory guidelines for pharmaceutical impurity handling.

How should Apixaban Impurity 47 (CAS: 536759-91-8) be stored?

Apixaban Impurity 47 should be stored in a cool, dry place away from light and moisture. Keep in a sealed, airtight container made of inert material, such as glass, to maintain stability. Avoid exposure to incompatible substances and ensure storage conditions comply with pharmaceutical safety standards.