(2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid

Basic Information

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CAS Number

52950-18-2

Molecular Formula

C8H7ClO3

Molecular Weight

186.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

119-121 °C

Boiling Point

350.3℃ at 760 mmHg

Density

1.480

Flash Point

165.7℃

Refractive Index

-124.5 ° (C=3, H2O)

Specific Rotation

-125 º (c=3, H2O)

SMILES

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C1=CC=C(C(=C1)C(C(=O)O)O)Cl

InChI

InChI=1S/C8H7ClO3/c9-6-4-2-1-3-5(6)7(10)8(11)12/h1-4,7,10H,(H,11,12)/t7-/m1/s1

InChIKey

RWOLDZZTBNYTMS-SSDOTTSWSA-N

LogP

1.4580000000000002

Topological Polar Surface Area

57.53 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

172

Safety Information

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GHS Hazard Pictograms

H317

H318

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

(r)-o-chloromandelic acid
(2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid
AS-12044
SCHEMBL24732
Z1255488133
AKOS016842462
MFCD00798429
52950-18-2
(R)-(-)-2-Chloromandelic acid, ChiPros(R), produced by BASF, 98%, >=97.5% (HPLC)
DTXSID10369958
(R)-(-)-2-Chloromandelic acid, 99%
Q-200024
NS00077611
J-650007
(2R)-2-(2-chlorophenyl)-2-hydroxy-acetic acid
R-(-)-2-Chloromandelic Acid
(R)-(2-chlorophenyl)hydroxyacetic acid
(R)-2-Chloromandelic acid
EN300-92105
CS-W016881
(R)-2'-Chloro-alpha-hydroxyphenylacetic Acid
AC-11667
AS-81148
(R)-2-(2-Chlorophenyl)-2-hydroxyacetic acid
RWOLDZZTBNYTMS-SSDOTTSWSA-N
C1663
2-Chloro-D-mandelic Acid
(R)-(-)-2-Chloromandelic acid
2-CHLORO-D-MANDELIC ACID
2-CHLORO-MANDELIC ACID (R)
(R)-2-CHLORO-ALPHA-HYDROXYPHENYLACETIC ACID

MDL Number

MFCD00798429

Customs Code

2918199090

FAQ

What is (2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid (CAS: 52950-18-2)?

(2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid, with CAS number 52950-18-2, is a chiral organic compound belonging to the class of hydroxyacetic acids. It has the chemical formula C8H9ClO3 and is characterized by its hydroxyl and carboxylic acid functional groups. This compound is known for its potential applications in medicinal chemistry due to its structural versatility and reactivity.

What are the main uses of (2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid (CAS: 52950-18-2)?

(2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid is primarily used in pharmaceutical research as a building block for drug development. It serves as an intermediate in the synthesis of various compounds, including potential antifungal and anti-inflammatory agents. Its unique structure also makes it valuable in chemical synthesis and organic chemistry studies.

Is (2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid (CAS: 52950-18-2) safe?

The safety of (2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid depends on exposure conditions and handling practices. It is considered potentially toxic and should be handled with appropriate protective measures, such as gloves and goggles. Safety data sheets (SDS) recommend avoiding inhalation and skin contact, and proper disposal is essential to meet environmental and health standards.

How should (2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid (CAS: 52950-18-2) be stored?

(2R)-2-(2-chlorophenyl)-2-hydroxyacetic acid should be stored in a cool, dry, and well-ventilated area, away from light. It is typically kept in a sealed container to prevent moisture absorption. Storage should maintain a temperature below 25°C and avoid exposure to humidity or direct sunlight to ensure stability and prolong shelf life.