N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide | CAS No. 52793-11-0
N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide
Basic Information
CAS Number
52793-11-0
Molecular Formula
C11H12ClNO3
Molecular Weight
241.67 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 5'-CHLORO-ORTHO-ACETOACETANISIDIDE
- NSC-165882
- O-ACETOACETANISIDIDE, 5'-CHLORO-
- NSC165882
- DTXSID6068806
- NSC 165882
- UNII-Y11EJY685E
- 5-CHLORO-2-METHOXYACETOACETANILIDE
- BIM-0009943.P001
- SMR000105788
- CHEMBL1339611
- AKOS000200119
- A829842
- Y11EJY685E
- FT-0621784
- Z56943783
- SMSF0013678
- CB13128
- EINECS 258-189-2
- 2-METHOXY-5-CHLOROACETOACETANILIDE
- MLS000109853
- W-111059
- N-(5-Chloro-2-methoxy-phenyl)-3-oxo-butyramide
- CBMicro_010213
- 5'-Chloro-2'-methoxyacetoacetanilide
- NS00007486
- CS-0307768
- Butanamide, N-(5-chloro-2-methoxyphenyl)-3-oxo-
- Q27294115
- EN300-06684
- EC 258-189-2
MDL Number
MFCD00026252
FAQ
What are the physical and chemical properties of N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0)?
N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0) is a white crystalline solid with a molecular weight of approximately 307.68 g/mol. It has a high solubility in polar solvents such as methanol and ethanol, and lower solubility in water. This compound is moderately reactive towards nucleophiles and can undergo hydrolysis under basic conditions. It is stable under normal storage conditions but should be protected from moisture and heat.
How is N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0) typically synthesized?
N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0) can be synthesized via a multi-step process involving the reaction of chloroacetyl chloride with 2-methoxyacetophenone, followed by acetylation. This process often utilizes a catalyst such as triethylamine to enhance yield. The reaction is typically conducted in an organic solvent like dichloromethane, and the product is purified by recrystallization.
What industries use N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0)?
N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0) finds applications in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also used in the polymer industry for the modification of polymer properties and in the sensor and semiconductor industries as a functional component.
What precautions should be taken when handling N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0)?
When handling N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide (CAS: 52793-11-0), it is crucial to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a well-ventilated area or under a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials, and the area should be decontaminated. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![N-[5-Chloro-2-(methoxyacetyl)phenyl]acetamide — JiangSuAiKangShengWuYiYaoYanFa Co Ltd](https://static.chemtradehub.com/suppliers/67cec9452b2de6e8e95a52fa/67cec9452b2de6e8e95a52fa-logo.webp){kind=logo}