(R)-(+)-1-(2-Naphthyl)ethanol

Basic Information

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CAS Number

52193-85-8

Molecular Formula

C12H12O

Molecular Weight

172.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

70.0 to 74.0 deg-C

Boiling Point

316.0±11.0 °C at 760 mmHg

Density

1.113

Flash Point

145.3±15.1 °C

Refractive Index

40 ° (C=1, MeOH)

Vapor Pressure

0.0±0.7 mmHg at 25°C

SMILES

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CC(C1=CC2=CC=CC=C2C=C1)O

InChI

InChI=1S/C12H12O/c1-9(13)11-7-6-10-4-2-3-5-12(10)8-11/h2-9,13H,1H3/t9-/m1/s1

InChIKey

AXRKCRWZRKETCK-SECBINFHSA-N

LogP

2.8931000000000013

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

167

Synonyms & References

English

(R)-(+)-1-(2-Naphthyl)ethanol
(+)-2-Naphthyl-1-ethanol
(R)-(+)-ALPHA-METHYL-2-NAPHTHALENE-METHA
(r)-(+)-alpha-methyl-2-naphthalenemethanol
(R)-(+)-α-Methyl-2-naphthalenemethanol
(1R)-1-naphthalen-2-ylethanol
(R)-(+)-alpha-methyl-2-naphthalene-methanol
(R)-(+)-2-(1-Hydroxyethyl)naphthalene
(+)-1-(2-Naphthyl)ethanol
(+)-alpha-Methyl-2-naphthalenemethanol
(R)-1-(Naphthalen-2-yl)ethanol
T72566
AKOS012670050
CS-0085781
BDBM50183596
DTXSID50426276
MFCD00075344
(R)-(+)-alpha-Methyl-2-naphthalenemethanol
AKOS015840846
(+)-(R)-1-Naphthalen-2-ylethanol
(1R)-1-(NAPHTHALEN-2-YL)ETHANOL
AXRKCRWZRKETCK-SECBINFHSA-N
(R)-1-(2-naphthyl)ethanol
EN300-85075
52193-85-8
N0784
(R)-(+)-1-(2-Naphthyl)ethanol, 98%
SCHEMBL445001
AS-60197
(1R)-1-(naphthalen-2-yl)ethan-1-ol
CHEMBL206560

MDL Number

MFCD00075344

FAQ

What are the physical and chemical properties of (R)-(+)-1-(2-Naphthyl)ethanol (CAS: 52193-85-8)?

(R)-(+)-1-(2-Naphthyl)ethanol is a crystalline compound with a molecular weight of approximately 172.23 g/mol. It is sparingly soluble in water but miscible with ethanol and other organic solvents. The compound exhibits good reactivity towards nucleophiles and can undergo substitution reactions. It also shows optical activity and is typically used in enantiomerically pure form.

How is (R)-(+)-1-(2-Naphthyl)ethanol (CAS: 52193-85-8) typically synthesized?

(R)-(+)-1-(2-Naphthyl)ethanol is often synthesized via the Wittig reaction, where 2-naphthylmethyltriphenylphosphonium bromide reacts with (R)-(+)-1-(2-naphthyl)ethanolate. The reaction is typically catalyzed by an organometallic reagent and provides high enantiomeric excess, with yields up to 85%.

What industries are (R)-(+)-1-(2-Naphthyl)ethanol (CAS: 52193-85-8) commonly used in?

(R)-(+)-1-(2-Naphthyl)ethanol is used in pharmaceuticals for the synthesis of chiral intermediates, polymers for optical applications, and sensors for detecting aromatic compounds. It is also utilized in the semiconductor industry for specific surface treatments and as a precursor in organic electronics.

What precautions should be taken when handling (R)-(+)-1-(2-Naphthyl)ethanol (CAS: 52193-85-8)?

When handling (R)-(+)-1-(2-Naphthyl)ethanol, it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. In the event of a spill, it should be cleaned up using absorbent materials and the area should be properly decontaminated. Always consult the Safety Data Sheet (SDS) for detailed handling procedures and emergency response guidelines.