Compound Q&A

How is (R)-(+)-1-(2-Naphthyl)ethanol (CAS: 52193-85-8) typically synthesized?

Answer

(R)-(+)-1-(2-Naphthyl)ethanol
(R)-(+)-1-(2-Naphthyl)ethanol is often synthesized via the Wittig reaction, where 2-naphthylmethyltriphenylphosphonium bromide reacts with (R)-(+)-1-(2-naphthyl)ethanolate. The reaction is typically catalyzed by an organometallic reagent and provides high enantiomeric excess, with yields up to 85%.

About

CAS No 52193-85-8
English Name (R)-(+)-1-(2-Naphthyl)ethanol
Molecular Formula C12H12O
Molecular Weight 172.23 g/mol
SMILES CC(C1=CC2=CC=CC=C2C=C1)O
InChIKey AXRKCRWZRKETCK-SECBINFHSA-N
Last Updated: 2025-10-22 12:37

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