Argatroban Impurity 75 HCl

Basic Information

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CAS Number

51298-62-5

Molecular Formula

C7H16ClN5O4

Molecular Weight

269.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

159-161 ºC

Boiling Point

383.5°C at 760 mmHg

Water Solubility

almost transparency

Solubility

H2O: 50 mg/mL

Refractive Index

15 ° (C=3, MeOH)

Specific Rotation

14.5 º (c=3, CH3OH)

SMILES

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COC(=O)C(CCCN=C(N)N[N+](=O)[O-])N.Cl

InChI

InChI=1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1

InChIKey

QBNXAGZYLSRPJK-JEDNCBNOSA-N

LogP

1.47960

Complexity

274

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

H-Arg(NO2)-Ome hydrochloride
(S)-Methyl 2-amino-5-(3-nitroguanidino)pentanoate hydrochloride
L-NAME HCl;H-Arg(NO2)-OMe HCl;N-Nitro-L-arginine methyl ester hydrochloride
DTXSID10199292
LNAME hydrochloride
L-Nitro Arginine Methyl Ester
AKOS015924237
CCG-222152
L-NAME hydrochloride
L-NG-Nitroarginine Methyl Ester (L-NAME)
EN300-204406
MLS001056504
N'-Nitro-L-arginine methyl ester hydrochloride
N.OMEGA.-NITRO-L-ARGININE METHYL ESTER HYDROCHLORIDE
L-NAME HCl
N 5751
TFX6A1PRZ1
(S)-Methyl 2-amino-5-(3-nitroguanidino)-pentanoate hydrochloride
Z2009977611
L-NAME (hydrochloride)
LP00848
Q27224955
Tox21_500848
L-NAME HCl
M03104
J-300042
QBNXAGZYLSRPJK-JEDNCBNOSA-N
FD10543
s2877
CHEBI:131182
NG-Nitro-L-arginine methyl ester hydrochloride

MDL Number

MFCD00039052

FAQ

What is Argatroban Impurity 75 HCl (CAS: 51298-62-5)?

Argatroban Impurity 75 HCl (CAS: 51298-62-5) is a chemical compound identified as an impurity during the synthesis of argatroban, an anticoagulant drug. It typically appears as a white to off-white crystalline solid and is soluble in water. The compound contains a sulfate group and a chloride ion, making it a hydrochloride salt. Its molecular formula is C19H27N3O7S·HCl, and it is characterized by its structural similarity to argatroban, which may affect its pharmacological properties.

What are the main uses of Argatroban Impurity 75 HCl (CAS: 51298-62-5)?

Argatroban Impurity 75 HCl (CAS: 51298-62-5) is primarily used in pharmaceutical research and quality control to identify and analyze impurities in argatroban production. It may also serve as a reference standard in drug development and analytical testing. Its applications include ensuring drug purity, supporting regulatory compliance, and aiding in the study of anticoagulant compounds. This impurity is relevant for assessing the safety and efficacy of argatroban in therapeutic settings.

Is Argatroban Impurity 75 HCl (CAS: 51298-62-5) safe?

Argatroban Impurity 75 HCl (CAS: 51298-62-5) is generally considered safe when handled properly in controlled environments. However, as a chemical impurity, it may pose risks such as skin or eye irritation. Safety precautions include wearing protective gloves, goggles, and lab coats. It is important to follow standard laboratory safety protocols and ensure proper ventilation. Limited toxicity data exists, so adherence to safety guidelines is crucial for minimizing exposure risks.

How should Argatroban Impurity 75 HCl (CAS: 51298-62-5) be stored?

Argatroban Impurity 75 HCl (CAS: 51298-62-5) should be stored in a cool, dry place, away from direct light. Maintain storage conditions at temperatures below 25°C and humidity levels below 60% to preserve stability. Use airtight, sealed containers to prevent moisture ingress. Avoid exposure to incompatible substances and store in a well-ventilated area. Proper storage ensures the compound remains chemically stable and safe for use in research or analytical processes.