N-(4-acetylphenyl)-3-chloropropanamide

Basic Information

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CAS Number

51256-02-1

Molecular Formula

C11H12ClNO2

Molecular Weight

225.67 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

152-155°C

SMILES

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CC(=O)C1=CC=C(C=C1)NC(=O)CCCl

InChI

InChI=1S/C11H12ClNO2/c1-8(14)9-2-4-10(5-3-9)13-11(15)6-7-12/h2-5H,6-7H2,1H3,(H,13,15)

InChIKey

CFTHHVYPCUMUNT-UHFFFAOYSA-N

LogP

2.456600000000001

Topological Polar Surface Area

46.17 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

235

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

n-(4-acetylphenyl)-3-chloropropanamide
N-(4-acetylphenyl)-3-chloro-Propanamide
3-chloro-propionic acid-(4-acetyl-anilide)
3-Chlor-propionsaeure-(4-acetyl-anilid)
p-acetyl-3-chloropropionanilide
EN300-25808
N-(4-acetylphenyl)-3-chloropropanamide
Z217707126
DB-030656
MFCD01313797
FS-4863
51256-02-1
AKOS001425495
CS-0215535
STL261825
A828506
DTXSID10383477
n-(4-acetyl-phenyl)-3-chloro-propionamide

MDL Number

MFCD01313797

Customs Code

2924299090

FAQ

What are the physical and chemical properties of N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1)?

N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1) is a white crystalline solid with a molecular weight of approximately 261.67 g/mol. It has a melting point of around 75-77°C and is slightly soluble in water. This compound is relatively chemically reactive, particularly towards nucleophiles. It is used in various synthetic applications due to its functional groups.

How is N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1) typically synthesized?

N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1) can be synthesized through the reaction of 4-acetylacetophenone and chloropropanol using a catalytic amount of an acid catalyst like sulfuric acid. The reaction yields the amide in moderate to good yield, with high selectivity towards the desired product.

What industries use N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1)?

N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1) is primarily used in pharmaceutical and polymer industries for the synthesis of intermediates and monomers. It also finds application in the development of sensors and as a reagent in organic synthesis for its functional groups.

What precautions should be taken when handling N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1)?

When handling N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or a fume hood to avoid inhalation of the compound. Store in a sealed container away from heat sources. In case of spill, neutralize with an appropriate agent and dispose of according to local regulations. Refer to the safety data sheet (SDS) for detailed information.