N-(4-acetylphenyl)-3-chloropropanamide(CAS: 51256-02-1)

N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1) is a white crystalline solid with a molecular weight of approximately 261.67 g/mol. It has a melting point of around 75-77°C and is slightly soluble in water. This compound is relatively chemically reactive, particularly towards nucleophiles. It is used in various synthetic applications due to its functional groups.

N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1) can be synthesized through the reaction of 4-acetylacetophenone and chloropropanol using a catalytic amount of an acid catalyst like sulfuric acid. The reaction yields the amide in moderate to good yield, with high selectivity towards the desired product.

N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1) is primarily used in pharmaceutical and polymer industries for the synthesis of intermediates and monomers. It also finds application in the development of sensors and as a reagent in organic synthesis for its functional groups.

When handling N-(4-acetylphenyl)-3-chloropropanamide (CAS: 51256-02-1), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or a fume hood to avoid inhalation of the compound. Store in a sealed container away from heat sources. In case of spill, neutralize with an appropriate agent and dispose of according to local regulations. Refer to the safety data sheet (SDS) for detailed information.