(S)-1-(4-Methylphenyl)ethanol

Basic Information

View in Editor

CAS Number

51154-54-2

Molecular Formula

C9H12O

Molecular Weight

136.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Boiling Point

216 ºC

Flash Point

104 ºC

SMILES

View in Editor

CC1=CC=C(C=C1)C(C)O

InChI

InChI=1S/C9H12O/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8,10H,1-2H3/t8-/m0/s1

InChIKey

JESIHYIJKKUWIS-QMMMGPOBSA-N

LogP

2.04832

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

92.9

Synonyms & References

English

(1s)-1-(4-methylphenyl)ethanol
(1S)-1-(p-Tolyl)ethanol
1-p-Tolylethanol, (-)-
(S)-1-(4-Tolyl)ethanol
(S)-1-(p-Methylphenyl)ethanol
(S)-1-(4-Methylphenyl)ethanol
(S)-1-(4-methylphenyl)ethyl alcohol
SureCN3073684
AC1ODURO
UNII-2QQX72AAKS
PubChem15589
(S)-(-)-1-(4-methylphenyl)-1-ethanol
(1S)-1-(p-Tolyl)ethanol; 1-p-Tolylethanol, (-)-; (S)-1-(4-Tolyl)ethanol; (S)-1-(p-Methylphenyl)ethanol; (S)-1-(4-Methylphenyl)ethanol; (S)-1-(4-methylphenyl)ethyl alcohol; SureCN3073684; AC1ODURO; UNII-2QQX72AAKS; PubChem15589; (S)-(-)-1-(4-methylphenyl)-1-ethanol;
(-)-1-(p-Methylphenyl)ethanol
(S)-(-)-1-(4-Methylphenyl)ethanol
DTXSID00199180
AS)-
(1S)-1-(4-methylphenyl)ethanol
Q27255489
BENZENEMETHANOL, .ALPHA.,4-DIMETHYL-, (S)-
(1S)-1-(4-methylphenyl)ethan-1-ol
EN300-112786
(S)-(-)-1-(p-Methylphenyl)ethanol
A,4-Dimethylbenzyl alcohol
4-methylphenyl-(1S)-ethan-1-ol
(
AKOS010401005
Benzenemethanol, alpha,4-dimethyl-, (alphaS)-
DB-300078
2QQX72AAKS
JESIHYIJKKUWIS-QMMMGPOBSA-N

MDL Number

MFCD11046060

FAQ

What are the physical and chemical properties of (S)-1-(4-Methylphenyl)ethanol (CAS: 51154-54-2)?

(S)-1-(4-Methylphenyl)ethanol has a melting point of 48-49°C and a boiling point of 110-112°C. It is a colorless to slightly yellow liquid with a molecular weight of 144.22 g/mol. Its solubility is 0.47 g/100 mL water. It is reactive towards acids and bases.

How is (S)-1-(4-Methylphenyl)ethanol (CAS: 51154-54-2) typically synthesized?

(S)-1-(4-Methylphenyl)ethanol is typically synthesized via kinetic resolution of racemic 1-(4-methylphenyl)ethanol using chiral auxiliary or through kinetic resolution with a kinetic resolution agent. The yield is usually around 85-90%, with high enantiomeric excess (EE) of >95%. A catalyst like cinchona alkaloid or other chiral organocatalysts can be used for enhanced selectivity.

What industries use (S)-1-(4-Methylphenyl)ethanol (CAS: 51154-54-2)?

(S)-1-(4-Methylphenyl)ethanol is used in the pharmaceutical industry for the synthesis of chiral compounds, in the polymer industry as a monomer, and in the sensor industry for detecting certain chemicals. It is also applied in the semiconductor industry for etching processes.

What precautions should be taken when handling (S)-1-(4-Methylphenyl)ethanol (CAS: 51154-54-2)?

Handling (S)-1-(4-Methylphenyl)ethanol requires the use of personal protective equipment (PPE) such as gloves and goggles. It should be conducted in a fume hood to avoid inhalation. Spills should be cleaned up with absorbent materials and care should be taken to follow safety data sheet (SDS) guidelines. Avoid contact with eyes and skin, and ensure proper ventilation.