Compound Q&A
How is (S)-1-(4-Methylphenyl)ethanol (CAS: 51154-54-2) typically synthesized?
Answer
(S)-1-(4-Methylphenyl)ethanol is typically synthesized via kinetic resolution of racemic 1-(4-methylphenyl)ethanol using chiral auxiliary or through kinetic resolution with a kinetic resolution agent. The yield is usually around 85-90%, with high enantiomeric excess (EE) of >95%. A catalyst like cinchona alkaloid or other chiral organocatalysts can be used for enhanced selectivity.
About
CAS No
51154-54-2
English Name
(S)-1-(4-Methylphenyl)ethanol
Molecular Formula
C9H12O
Molecular Weight
136.19 g/mol
SMILES
CC1=CC=C(C=C1)C(C)O
InChIKey
JESIHYIJKKUWIS-QMMMGPOBSA-N
Last Updated: 2026-03-10 19:33
