2-Bromo-6-methoxynaphthalene (Naproxen Impurity N)

Basic Information

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CAS Number

5111-65-9

Molecular Formula

C11H9BrO

Molecular Weight

237.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

106-109 °C

Boiling Point

164°C/3mmHg

Water Solubility

Soluble in DMSO. Insoluble in water.

Flash Point

160-164℃/3mm

Refractive Index

1.5290 (estimate)

Vapor Pressure

0.0±0.7 mmHg at 25°C

SMILES

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COC1=CC2=C(C=C1)C=C(C=C2)Br

InChI

InChI=1S/C11H9BrO/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h2-7H,1H3

InChIKey

AYFJBMBVXWNYLT-UHFFFAOYSA-N

LogP

3.6109000000000018

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

172

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

AC-8343
NCGC00253733-01
6-Methoxy-2-bromonaphthalene
2-bromo-6-methoxy naphthalene
DTXSID10199116
2-Bromo-6-methoxy-Naphthalene
2-Bromo-6-methoxynaphthalene; Naproxen Imp. N (EP); Naproxen Impurity N
2-bromo-6-methoxynapthalene
6-Bromo-2-naphthylmethylether
2-Bromo-6-methoxynaphthalene (Naproxen Impurity N)
S19T080MRG
Q-200551
2-bromo-6-methoxynaphthalen
2-Bromo-6-methoxynaphthalene, 97%
EN300-203818
FT-0611512
2-methoxy-6-bromo-naphthalene
PD055461
SY011231
Q27288440
NSC3236
AM20060647
Naphthalene, 2-bromo-6-methoxy-
NAPROXEN SODIUM IMPURITY N [EP IMPURITY]
EINECS 225-837-0
6-Bromo-2-methoxynaphthalene
NAPROXEN IMPURITY N [EP IMPURITY]
2-METHOXY-6-BROMONAPHTHALENE
HY-Y0038
AI3-18465
5111-65-9

MDL Number

MFCD00004062

Customs Code

2909309090

FAQ

What is 2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9)?

2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9) is a chemical compound with the molecular formula C12H10BrNO. It is an impurity found in naproxen, a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief and reducing inflammation.

What are the main uses of 2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9)?

2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9) is primarily used as an impurity in the pharmaceutical industry, particularly in the synthesis and quality control of naproxen. It is not used as a standalone compound but is monitored to ensure the purity of naproxen drugs.

Is 2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9) safe?

2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9) is generally considered safe when used under proper handling conditions. However, it is important to follow safety guidelines, such as wearing appropriate personal protective equipment (PPE) and handling it in a well-ventilated area to avoid inhalation and skin contact.

How should 2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9) be stored?

2-Bromo-6-methoxynaphthalene (CAS: 5111-65-9) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation and ensure purity. Proper storage conditions are crucial to maintain its stability and safety during handling and use.