Norethindrone acetate

Basic Information

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CAS Number

51-98-9

Molecular Formula

C22H28O3

Molecular Weight

330.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

160.0 to 165.0 deg-C

Boiling Point

454.7°C at 760 mmHg

Flash Point

197.1°C

Refractive Index

-34 ° (C=1, Dioxane)

Vapor Pressure

1.87E-08mmHg at 25°C

SMILES

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CC(=O)OC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34)C)C#C

InChI

InChI=1S/C21H30O3/c1-13(22)24-21(3)11-9-19-18-6-4-14-12-15(23)5-7-16(14)17(18)8-10-20(19,21)2/h12,16-19H,4-11H2,1-3H3/t16-,17+,18+,19-,20+,21+/m0/s1

InChIKey

PPVVBFLQFMBPFG-ZVZGYBOSSA-N

LogP

4.450000000000004

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

695

Safety Information

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GHS Hazard Pictograms

H351

Hazard Statement

H351 Suspected of causing cancer
Carcinogenicity

Synonyms & References

English

17-Acetoxy-19-nor-17-alpha-pregn-4-en-20-yn-3-one
(17beta)-17-ethynyl-3-oxoestr-4-en-17-yl acetate
19-Nor-17alpha-ethynyltestosterone Acetate
19-Nor-17alpha-pregn-4-en-20-yn-3-one, 17-hydroxy-, acetate
HY-B1710
NORETHINDRONE ACETATE [USP MONOGRAPH]
IMONTRJLAWHYGT-ZCPXKWAGSA-N
NORETHINDRONE ACETATE [MI]
Orlutate
Norethindrone acetate (USP)
17-Acetoxy-19-nor-17alpha-pregn-4-en-20-yn-3-one
C22H28O3
(17-alpha)-17-(Acetyloxy)-19-norpregn-4-en-20-yn-3-one
T72561
Norlutin acetate
Progylut
17beta-Acetoxy-19-nor-17alpha-pregn-4-en-20-yn-3-one
Norethynyltestosterone acetate
Norethindrone acetate
HMS3259A16
MYFEMBREE COMPONENT NORETHINDRONE ACETATE
NSC 22844
NORETHINDRONE ACETATE [VANDF]
17alpha-Ethynyl-17beta-acetoxy-19-norandrost-4-en-3-one
19-nor-17.alpha.-Pregn-4-en-20-yn-3-one, 17-acetoxy-
Norlutine acetate
AKOS016010517
ACTIVELLA COMPONENT NORETHINDRONE ACETATE
Norethindrone acetate, United States Pharmacopeia (USP) Reference Standard
BCP11908
NORETHINDRONE ACETATE COMPONENT OF ORIAHNN

MDL Number

MFCD00271615

Customs Code

2915299090

FAQ

What are the physical and chemical properties of Norethindrone acetate (CAS: 51-98-9)?

Norethindrone acetate (CAS: 51-98-9) is a white to off-white crystalline powder. Its molecular weight is approximately 328.4 g/mol. It is sparingly soluble in water and more soluble in organic solvents. Chemically, it is stable under normal conditions but may be sensitive to heat and light. It is used in hormonal contraceptives and other medical applications.

How is Norethindrone acetate (CAS: 51-98-9) typically synthesized?

Norethindrone acetate (CAS: 51-98-9) is typically synthesized through a multi-step process starting from androstenedione or other steroid precursors. Common methods include acetylation reactions followed by various ring transformations and dehydrogenations. The synthesis often involves the use of catalysts and requires specific reaction conditions to achieve high selectivity and yield.

What industries use Norethindrone acetate (CAS: 51-98-9)?

Norethindrone acetate (CAS: 51-98-9) is primarily used in the pharmaceutical industry for hormonal contraceptives and other medical applications. It is also used in the research and development of other steroid-based drugs. Its application in polymer and sensor technologies is limited but ongoing research explores its potential in these areas.

What precautions should be taken when handling Norethindrone acetate (CAS: 51-98-9)?

When handling Norethindrone acetate (CAS: 51-98-9), it is important to use personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up carefully following standard laboratory procedures. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.