His-Pro-Phe-His-Leu-D-Leu-Val-Tyr | CAS No. 50410-01-0
His-Pro-Phe-His-Leu-D-Leu-Val-Tyr
Basic Information
CAS Number
50410-01-0
Molecular Formula
C37H62N10O12
Molecular Weight
838.95 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
804.89°C (rough estimate)
Refractive Index
1.6000 (estimate)
Synonyms & References
English
- h-his-pro-phe-his-leu-d-leu-val-tyr-oh
- H-His-Pro-Phe-His-Leu-D-Leu-Val-Tyr-NH2
- His-Pro-Phe-His-Leu-D-Leu-Val-Tyr
- HIS-PRO-PHE-HIS-LEU-D-LEU-VAL-TYR-NH2
- histidine-proline-phenylalanine-histidine-leucine-valine
- HPFHLLVY
- RENIN INHIBITOR PEPTIDE
- (2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
- 50410-01-0
MDL Number
MFCD00133401
FAQ
What are the physical and chemical properties of His-Pro-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0)?
His-Pro-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0) is a complex cyclic peptide with a molecular weight of approximately 1139.4 Da. It is poorly soluble in water but soluble in organic solvents. This peptide is prone to hydrolysis under acidic or basic conditions, making it susceptible to degradation. It forms a crystalline structure and can be analyzed by HPLC and MS techniques.
How is His-Pro-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0) typically synthesized?
His-Pro-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0) is synthesized using solid-phase peptide synthesis (SPPS). Commonly, the peptide is assembled using Fmoc chemistry, with stepwise coupling of amino acids. The synthesis typically yields a 90% purity with good selectivity. The final product is isolated by HPLC and characterized by mass spectrometry.
What industries use His-Pro-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0)?
His-Pro-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0) is used in the pharmaceutical industry for its potential as a bioactive peptide. It is also explored in biotechnology for its use in diagnostic tools and in the development of new drug candidates. Additionally, it has applications in the polymer industry for its ability to enhance certain polymer properties.
What precautions should be taken when handling His-Pro-Phe-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0)?
When handling His-Pro-Phe-His-Leu-D-Leu-Val-Tyr (CAS: 50410-01-0), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. If a spill occurs, it should be cleaned up using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed information on handling and disposing of the compound safely.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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