7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine | CAS No. 50351-80-9

7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine

Basic Information

CAS Number

50351-80-9

Molecular Formula

C11H15NO

Molecular Weight

177.25 g/mol

AD

Basic Physical Properties

COc1ccc2CCNCCc2c1

InChI

InChI=1S/C11H15NO/c1-13-11-3-2-9-4-6-12-7-5-10(9)8-11/h2-3,8,12H,4-7H2,1H3

InChIKey

VWLWWBQMNIAARP-UHFFFAOYSA-N

LogP

1.3834

Topological Polar Surface Area

21.259999999999998 Ų

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

160

Synonyms & References

English

  • 2,3,4,5-TETRAHYDRO-7-METHOXY-1H-BENZO[D]AZEPINE
  • 1H-3-Benzazepine, 2,3,4,5-tetrahydro-7-methoxy-
  • 7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine
  • 1,2,4,5-tetrahydro-7-methoxy-3H-3-benzazepine
  • 1H-3-Benzazepine,2,3,4,5-tetrahydro-7-methoxy
  • 7-methoxy-2,3,4,5-tetrahydro-1H-benzazepine
  • 7-METHOXY-2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
  • AMY27291
  • SB17681
  • 7-methoxy-1H,2H,3H,4H,5H-benzo[d]azepine
  • 7-methoxy-2,3,4,5-tetrahydro-1H-benz[d]azepine
  • 7-Methoxy-2,3,4,5-tetrahydro-1 H-benzo[d]azepine

MDL Number

MFCD08703282

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine (CAS: 50351-80-9)?

7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine is a white crystalline solid with a molecular weight of approximately 221.23 g/mol. It is slightly soluble in water and has a low boiling point. The compound is relatively stable under normal conditions but can react with strong acids or bases. It is often stored in airtight containers to prevent degradation.

How is 7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine (CAS: 50351-80-9) typically synthesized?

7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine is commonly synthesized via a multi-step process involving ring expansion of a benzazepine derivative followed by methylation. The reaction is typically catalyzed by a Lewis acid such as aluminum chloride, and the yield is around 70-80%. The synthetic route is well-documented in the literature and involves careful control of reaction conditions to achieve high selectivity.

What industries use 7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine (CAS: 50351-80-9)?

7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine is primarily used in the pharmaceutical industry for developing new drugs. It is also utilized in the polymer industry as a raw material for synthesizing polymeric materials with specific properties. Additionally, it has applications in the production of sensors and semiconductors due to its unique chemical structure.

What precautions should be taken when handling 7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine (CAS: 50351-80-9)?

When handling 7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. In case of spillage, it is recommended to use appropriate spill cleanup kits and follow safety data sheet (SDS) guidelines for proper disposal.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...