7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine(CAS: 50351-80-9)

7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine is a white crystalline solid with a molecular weight of approximately 221.23 g/mol. It is slightly soluble in water and has a low boiling point. The compound is relatively stable under normal conditions but can react with strong acids or bases. It is often stored in airtight containers to prevent degradation.

7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine is commonly synthesized via a multi-step process involving ring expansion of a benzazepine derivative followed by methylation. The reaction is typically catalyzed by a Lewis acid such as aluminum chloride, and the yield is around 70-80%. The synthetic route is well-documented in the literature and involves careful control of reaction conditions to achieve high selectivity.

7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine is primarily used in the pharmaceutical industry for developing new drugs. It is also utilized in the polymer industry as a raw material for synthesizing polymeric materials with specific properties. Additionally, it has applications in the production of sensors and semiconductors due to its unique chemical structure.

When handling 7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. In case of spillage, it is recommended to use appropriate spill cleanup kits and follow safety data sheet (SDS) guidelines for proper disposal.