(5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one | CAS No. 503090-99-1
(5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one
Basic Information
CAS Number
503090-99-1
Molecular Formula
C20H25NO4
Molecular Weight
343.42 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
540.5±50.0 °C(Predicted)
Density
1.37±0.1 g/cm3(Predicted)
Synonyms & References
English
- Naltrexone EP Impurity H
- Naltrexone EP Impuirty H
- LTREXONE HYDROCHLORIDE - IMPURITY H
- Naltrexone-008
- N-Butyl Noroxymorphone (1.0 mg/ml in Methanol)
- Morphinan-6-one, 17-butyl-4,5-epoxy-3,14-dihydroxy-, (5α)- (9CI)
- Morphinan-6-one, 17-butyl-4,5-epoxy-3,14-dihydroxy-, (5a)-
FAQ
What are the physical and chemical properties of (5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one (CAS: 503090-99-1)?
The compound (5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one is a crystalline solid with a molecular weight of approximately 365.48 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and ethanol. The compound is known for its epoxide functionality and hydroxyl groups, which make it reactive towards nucleophiles and electrophiles. It is susceptible to hydrolysis under basic conditions.
How is (5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one (CAS: 503090-99-1) typically synthesized?
(5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one can be synthesized via a multi-step process involving the epoxidation of a precursor, followed by ring opening and substitution reactions. Common catalysts include transition metals like palladium, and the overall yield can range from 50% to 70%, depending on the reaction conditions and optimization of the process.
What industries use (5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one (CAS: 503090-99-1)?
(5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one is primarily used in the pharmaceutical industry as an intermediate in the synthesis of morphinan derivatives. It is also utilized in the production of certain polymers and materials due to its functional groups, which can be further modified to impart specific properties.
What precautions should be taken when handling (5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one (CAS: 503090-99-1)?
When handling (5alpha)-17-Butyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and following safety protocols. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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