2-(Benzyloxy)-2-(2-naphthyl)acetonitrile | CAS No. 500372-25-8
2-(Benzyloxy)-2-(2-naphthyl)acetonitrile
Basic Information
CAS Number
500372-25-8
Molecular Formula
C19H15NO
Molecular Weight
17.03 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 2-(BENZYLOXY)-2-(2-NAPHTHYL)ACETONITRILE
- 2-(2-Naphthyl)-2-(phenylmethoxy)-ethanenitrile
- 2-naphthalen-2-yl-2-phenylmethoxyacetonitrile
- 2-(Benzyloxy)-2-(naphthalen-2-yl)acetonitrile
- DTXSID40440461
- 2-(2-Naphthyl)-2-(phenylmethoxy)-ethanenitril
- DB-260098
- 2-(Benzyloxy)-2-(2-naphthyl)acetonitrile, >=95.0%
- 2-(2-phthyl)-2-(phenylmethoxy)-ethanenitrile
- J-100220
- SCHEMBL6749962
- 2-(Benzyloxy)-2-(2-naphthyl)acetonitrile
- 500372-25-8
- MFCD09752029
MDL Number
MFCD09752029
FAQ
What are the physical and chemical properties of 2-(Benzyloxy)-2-(2-naphthyl)acetonitrile (CAS: 500372-25-8)?
2-(Benzyloxy)-2-(2-naphthyl)acetonitrile (CAS: 500372-25-8) is a crystalline solid with a molecular weight of approximately 283.27 g/mol. It has a low solubility in water but is soluble in common organic solvents such as dichloromethane and methanol. The compound is moderately reactive, showing electrophilic character towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be handled with care due to its reactivity.
How is 2-(Benzyloxy)-2-(2-naphthyl)acetonitrile (CAS: 500372-25-8) typically synthesized?
2-(Benzyloxy)-2-(2-naphthyl)acetonitrile is typically synthesized via a multi-step process involving the coupling of 2-benzyloxybenzonitrile with 2-naphthylboronic acid using Pd(PPh3)4 as a catalyst in the presence of a base like sodium carbonate. The reaction proceeds in a solvent like toluene or dioxane under microwave heating to enhance yield and selectivity. The final product is purified by recrystallization from ethanol.
What industries use 2-(Benzyloxy)-2-(2-naphthyl)acetonitrile (CAS: 500372-25-8)?
2-(Benzyloxy)-2-(2-naphthyl)acetonitrile (CAS: 500372-25-8) finds applications in the pharmaceutical industry, where it serves as a precursor for synthesizing more complex molecules. It is also used in the development of sensors and semiconductors due to its unique electronic properties. Its aromatic structure and functional groups make it a versatile intermediate in organic synthesis.
What precautions should be taken when handling 2-(Benzyloxy)-2-(2-naphthyl)acetonitrile (CAS: 500372-25-8)?
When handling 2-(Benzyloxy)-2-(2-naphthyl)acetonitrile (CAS: 500372-25-8), it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and ignition sources. Spills should be handled with care, using appropriate spill kits or absorbents. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
