(11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione

Basic Information

View in Editor

CAS Number

50-22-6

Molecular Formula

C21H30O4

Molecular Weight

346.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

Powder

Melting Point

181.0 to 184.0 deg-C

Boiling Point

529.2°C at 760 mmHg

Flash Point

9℃

Solubility

N/A

Refractive Index

1.4430 (estimate)

Specific Rotation

D15 +223° (c = 1.1 in alc)

SMILES

View in Editor

OCC(=O)[C@H]1CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C

InChI

InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

InChIKey

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

LogP

2.6667000000000014

Topological Polar Surface Area

74.6 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

638

Safety Information

View Safety Information

GHS Hazard Pictograms

H317

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

Storage Conditions

2-8℃

Stability

Stable, but light sensitive. Incompatible with strong oxidizing agents.

Synonyms & References

English

CORTICOSTERONE
NSC-9705
compoundb
Corticosteron
KENDALL'S 'B'
Reichstein's B
17-Deoxycortisol
CORTICOSTERONE(RG)
KENDALL'S COMPOUND B
(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Corticosterone solution
11β,21-Dihydroxyprogesterone
11beta,21-Dihydroxyprogesterone
4-Pregnene-11beta,21-diol-3,20-dione
NSC 9705
Reichstein's substance H
Compound B
11-Hydroxycorticoaldosterone
11,21-Dihydroxyprogesterone
11,12-Dihydroxyprogesterone
NSC9705
11-be
Kendall's compound B
Corticosterone
(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

MDL Number

MFCD00037715

FAQ

What is (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione (CAS: 50-22-6)?

(11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione, with CAS number 50-22-6, is a steroid compound classified as a pregnane. It has the molecular formula C22H32O4 and is known for its hydroxyl groups at positions 11 and 21, along with ketone functionalities at 3 and 20. This compound is commonly used in research and pharmaceutical applications due to its structural similarity to corticosteroids.

What are the main uses of (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione (CAS: 50-22-6)?

(11beta)-11,21-Dihdroxypregn-4-ene-3,20-dione (CAS: 50-22-6) is primarily used in the synthesis of corticosteroids and other steroid derivatives. It serves as an intermediate in pharmaceutical research for developing anti-inflammatory and immunosuppressive drugs. Additionally, it is utilized in biochemical studies to understand steroid metabolism and hormonal activity.

Is (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione (CAS: 50-22-6) safe?

(11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione (CAS: 50-22-6) is generally considered safe when handled properly in controlled laboratory settings. However, as a chemical compound, it may pose risks if exposed to skin, eyes, or inhaled. Safety precautions include wearing appropriate personal protective equipment (PPE) and following standard laboratory safety protocols to minimize potential health hazards.

How should (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione (CAS: 50-22-6) be stored?

(11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione (CAS: 50-22-6) should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is important to maintain low humidity levels and protect it from light exposure to ensure stability. The compound should be kept in a sealed, inert container to prevent degradation and contamination.