3-(Bromomethyl)pyridine hydrobromide (1:1)

Basic Information

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CAS Number

4916-55-6

Molecular Formula

C6H7Br2N

Molecular Weight

252.94 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

150-155 °C

Flash Point

114.2℃

SMILES

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C1=CC(=CN=C1)CBr.Br

InChI

InChI=1S/C6H6BrN.BrH/c7-4-6-2-1-3-8-5-6;/h1-3,5H,4H2;1H

InChIKey

FNHPUOJKUXFUKN-UHFFFAOYSA-N

LogP

2.5544000000000007

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

65.5

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

4916-55-6
3-(bromomethyl)pyridine monohydrobromide
FG-0490
AC-2598
STR07573
3-bromomethylpyridine hydrogenbromide
Pyridine, 3-(bromomethyl)-, hydrobromide
NSC338478
3-(bromomethyl)-pyridine hydrobromide
SY002302
3-(brommethyl)pyridine-hbr
NSC-338478
SB37338
AKOS005146237
A871837
HY-W004131
3-Bromomethylpyridine (hydrobromide)
3-(Bromomethyl)pyridineHydrobromide
AM20061249
3-(bromomethyl)pyridin-1-ium bromide
3-(Bromomethyl)pyridine hydrobromide, 97%
EN300-44247
3-(bromomethyl)pyridine, hydrobromide
DTXSID10507530
B2170
3-(BROMOMETHYL)PYRIDINE HBR
3-bromomethyl-pyridine hydrobromide
3-(bromomethyl)pyridine;hydrobromide
3-bromomethyl pyridine hydrobromide
3-(Bromomethyl)pyridine--hydrogen bromide (1/1)
3-Bromomethylpyridine hydrobromide

MDL Number

MFCD01321314

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6)?

3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6) is a crystalline solid with a molecular weight of approximately 263.03 g/mol. It has a solubility of about 40 mg/mL in water and is soluble in common organic solvents like ethanol and acetone. It is moderately reactive with nucleophiles and has limited reactivity with electrophiles. The compound is stable under normal conditions but should be stored away from moisture to prevent hydrolysis.

How is 3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6) typically synthesized?

3-(Bromomethyl)pyridine hydrobromide is typically synthesized by bromination of 3-methylpyridine followed by hydrobromination. The reaction involves the bromination of 3-methylpyridine using bromine in the presence of a base like sodium hydride. Hydrobromination is then performed using hydrogen bromide under anhydrous conditions to form the target compound. The yield is around 70-80%, and the process is carried out with a high level of selectivity.

What industries use 3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6)?

3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also has applications in the polymer industry for the production of functionalized polymers. Additionally, it can be used in the development of sensors and semiconductors due to its chemical properties, though its use in these sectors is less common.

What precautions should be taken when handling 3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6)?

When handling 3-(Bromomethyl)pyridine hydrobromide (CAS: 4916-55-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a dry, cool, and well-ventilated area to prevent hydrolysis. Fume hoods should be used during preparation and handling to minimize exposure to fumes. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.